Systemic inflammation is elevated among both HIV-uninfected and HIV-infected young MSM

Ethan Morgan; Harry E. Taylor; Daniel Timothy Ryan; Richard Thomas D'Aquila; Brian Mustanski

doi:10.1097/QAD.0000000000002093

Systemic inflammation is elevated among both HIV-uninfected and HIV-infected young MSM

Ethan Morgan, Harry E. Taylor, Daniel Timothy Ryan, Richard Thomas D'Aquila, Brian Mustanski

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Abstract

: Evidence suggests that systemic inflammation increases due to HIV infection. C-reactive protein (CRP), interleukin (IL)-6 and tumour necrosis factor (TNF)-α values were compared between HIV-positive and HIV-negative young MSM and transgender women. CRP values were more than 3 mg/l among 49.8% of participants. HIV status was not significantly associated with CRP nor IL-6. TNF-α was significantly higher among HIV-positive participants. These results suggest the need for further study of the causes and health consequences of elevated systemic inflammation among this population.

Original language	English (US)
Pages (from-to)	757-759
Number of pages	3
Journal	AIDS (London, England)
Volume	33
Issue number	4
Early online date	Nov 27 2018
DOIs	https://doi.org/10.1097/QAD.0000000000002093
State	Published - Mar 15 2019

ASJC Scopus subject areas

Immunology and Allergy
Immunology
Infectious Diseases

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1097/QAD.0000000000002093

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title = "Systemic inflammation is elevated among both HIV-uninfected and HIV-infected young MSM",

abstract = ": Evidence suggests that systemic inflammation increases due to HIV infection. C-reactive protein (CRP), interleukin (IL)-6 and tumour necrosis factor (TNF)-α values were compared between HIV-positive and HIV-negative young MSM and transgender women. CRP values were more than 3 mg/l among 49.8% of participants. HIV status was not significantly associated with CRP nor IL-6. TNF-α was significantly higher among HIV-positive participants. These results suggest the need for further study of the causes and health consequences of elevated systemic inflammation among this population.",

author = "Ethan Morgan and Taylor, {Harry E.} and Ryan, {Daniel Timothy} and D'Aquila, {Richard Thomas} and Brian Mustanski",

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T1 - Systemic inflammation is elevated among both HIV-uninfected and HIV-infected young MSM

AU - Morgan, Ethan

AU - Taylor, Harry E.

AU - Ryan, Daniel Timothy

AU - D'Aquila, Richard Thomas

AU - Mustanski, Brian

PY - 2019/3/15

Y1 - 2019/3/15

N2 - : Evidence suggests that systemic inflammation increases due to HIV infection. C-reactive protein (CRP), interleukin (IL)-6 and tumour necrosis factor (TNF)-α values were compared between HIV-positive and HIV-negative young MSM and transgender women. CRP values were more than 3 mg/l among 49.8% of participants. HIV status was not significantly associated with CRP nor IL-6. TNF-α was significantly higher among HIV-positive participants. These results suggest the need for further study of the causes and health consequences of elevated systemic inflammation among this population.

AB - : Evidence suggests that systemic inflammation increases due to HIV infection. C-reactive protein (CRP), interleukin (IL)-6 and tumour necrosis factor (TNF)-α values were compared between HIV-positive and HIV-negative young MSM and transgender women. CRP values were more than 3 mg/l among 49.8% of participants. HIV status was not significantly associated with CRP nor IL-6. TNF-α was significantly higher among HIV-positive participants. These results suggest the need for further study of the causes and health consequences of elevated systemic inflammation among this population.

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JO - AIDS

JF - AIDS

IS - 4

ER -

Systemic inflammation is elevated among both HIV-uninfected and HIV-infected young MSM

Abstract

ASJC Scopus subject areas

UN SDGs

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