Systemic sclerosis (scleroderma)

Shervin Assassi, John Varga

Research output: Chapter in Book/Report/Conference proceedingChapter


Systemic sclerosis or scleroderma is a multisystem, autoimmune disease with prominent fibrotic and vasculopathic features. Clinically, it is associated with high morbidity and mortality, although the disease course can be highly variable. In this chapter, we provide an overview of the current knowledge about the epidemiology, pathogenesis, clinical features, as well as monitoring and treatment strategies of systemic sclerosis.

Original languageEnglish (US)
Title of host publicationThe Autoimmune Diseases
Number of pages31
ISBN (Electronic)9780128121023
ISBN (Print)9780128122426
StatePublished - Jan 1 2019


  • Scleroderma
  • Systemic sclerosis

ASJC Scopus subject areas

  • Medicine(all)
  • Immunology and Microbiology(all)


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