TARDBP 3′-UTR variant in autopsy-confirmed frontotemporal lobar degeneration with TDP-43 proteinopathy

Keyphrases

• 3′-untranslated Region (3′-UTR) 100%
• Frontotemporal Lobar Degeneration 100%
• TAR DNA-binding Protein 43 (TDP-43) 100%
• TARDBP 100%
• Autopsy-confirmed 100%
• Frontotemporal Dementia 60%
• Clinical Phenotype 40%
• Amyotrophic Lateral Sclerosis 40%
• Sequence Analysis 20%
• Neuropathology 20%
• Heterogeneous Phenotype 20%
• Disease-specific 20%
• Brain Tissue 20%
• Gene Expression Analysis 20%
• Functional Significance 20%
• Control Subjects 20%
• Autopsy 20%
• Allele-specific Expression 20%
• Molecular Pathology 20%
• Proband 20%
• Pathogenic mutations 20%
• TARDBP Gene 20%
• Quantitative Gene Expression 20%
• Allele-specific Amplification 20%

Biochemistry, Genetics and Molecular Biology

• Proteinopathy 100%
• TARDBP 100%
• Transactive Response Dna Binding Protein-43 100%
• Untranslated Region 100%
• Allele 50%
• Proband 16%
• Gene Expression Profiling 16%
• Messenger RNA 16%

Neuroscience

• Untranslated Region 100%
• Amyotrophic Lateral Sclerosis 100%
• Frontal Variant Frontotemporal Dementia 42%
• Expression Analysis 14%
• Gene Expression 14%
• Messenger RNA 14%