Targeted cancer nanotherapy

Gloria J. Kim*, Shuming Nie

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

61 Scopus citations

Abstract

Different nanometer-sized particles, which have optical, electronic, and structural properties that are not available from either individual molecules or bulk solids, are developed for Cancer nanotherapy. When linked with tumor-targeting moieties, such as tumor-specific ligands or monoclonal antibodies, these nanoparticles can be used to target cancer-specific receptors, tumor antigens and tumor vasculatures with high affinity and precision. Nanoscale devices can interact with biomolecules on cell surface and within the cells in a noninvasive manner, leaving the behavior and biochemical properties of those molecules intact. Nanoparticles have more surface areas and functional groups that can be linked to multiple optical, radioisotopic diagnostics.

Original languageEnglish (US)
Pages (from-to)28-33
Number of pages6
JournalMaterials Today
Volume8
Issue number8 SUPPL.
DOIs
StatePublished - Aug 2005

ASJC Scopus subject areas

  • Materials Science(all)
  • Condensed Matter Physics
  • Mechanics of Materials
  • Mechanical Engineering

Fingerprint Dive into the research topics of 'Targeted cancer nanotherapy'. Together they form a unique fingerprint.

Cite this