Targeted muscle reinnervation and advanced prosthetic arms

Jennifer E. Cheesborough, Lauren H. Smith, Todd A. Kuiken, Gregory A. Dumanian*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

113 Scopus citations


Targeted muscle reinnervation (TMR) is a surgical procedure used to improve the control of upper limb prostheses. Residual nerves from the amputated limb are transferred to reinnervate new muscle targets that have otherwise lost their function. These reinnervated muscles then serve as biological amplifiers of the amputated nerve motor signals, allowing for more intuitive control of advanced prosthetic arms. Here the authors provide a review of surgical techniques for TMR in patients with either transhumeral or shoulder disarticulation amputations. They also discuss how TMR may act synergistically with recent advances in prosthetic arm technologies to improve prosthesis controllability. Discussion of TMR and prosthesis control is presented in the context of a 41-year-old man with a left-side shoulder disarticulation and a right-side transhumeral amputation. This patient underwent bilateral TMR surgery and was fit with advanced pattern-recognition myoelectric prostheses.

Original languageEnglish (US)
Pages (from-to)62-72
Number of pages11
JournalSeminars in Plastic Surgery
Issue number1
StatePublished - Feb 2015


  • amputation
  • prosthetic limb
  • shoulder disarticulation
  • targeted muscle reinnervation
  • transhumeral amputation

ASJC Scopus subject areas

  • Surgery


Dive into the research topics of 'Targeted muscle reinnervation and advanced prosthetic arms'. Together they form a unique fingerprint.

Cite this