Targeted Muscle Reinnervation as a Strategy for Neuroma Prevention

Jason H. Ko; Peter S. Kim; Douglas G. Smith

doi:10.1201/b15079-9

Targeted Muscle Reinnervation as a Strategy for Neuroma Prevention

Jason H. Ko, Peter S. Kim, Douglas G. Smith

Research output: Chapter in Book/Report/Conference proceeding › Chapter

5 Scopus citations

Abstract

When a peripheral nerve is transected, a bulbous swelling, or neuroma, will develop at the severed end of the nerve (Figure 4.1). Neuromas consist of disorganized, chaotic axons encased in significant scar and fibrous tissue. They are frequently sensitive to pressure and other forms of mechanical irritation, causing a focal pain that is often difficult to treat. By providing a distal muscle target for the proximal transected axons to grow into, targeted muscle reinnervation (TMR) may represent a novel technique for the prevention and treatment of neuromas. In this chapter, we will discuss the pathophysiology.

Original language	English (US)
Title of host publication	Targeted Muscle Reinnervation
Subtitle of host publication	A Neural Interface for Artificial Limbs
Publisher	CRC Press
Pages	45-66
Number of pages	22
ISBN (Electronic)	9781439860816
ISBN (Print)	9781138198647
DOIs	https://doi.org/10.1201/b15079-9
State	Published - Jan 1 2013
Externally published	Yes

ASJC Scopus subject areas

General Medicine
General Biochemistry, Genetics and Molecular Biology
General Physics and Astronomy

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10.1201/b15079-9

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title = "Targeted Muscle Reinnervation as a Strategy for Neuroma Prevention",

abstract = "When a peripheral nerve is transected, a bulbous swelling, or neuroma, will develop at the severed end of the nerve (Figure 4.1). Neuromas consist of disorganized, chaotic axons encased in significant scar and fibrous tissue. They are frequently sensitive to pressure and other forms of mechanical irritation, causing a focal pain that is often difficult to treat. By providing a distal muscle target for the proximal transected axons to grow into, targeted muscle reinnervation (TMR) may represent a novel technique for the prevention and treatment of neuromas. In this chapter, we will discuss the pathophysiology.",

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AB - When a peripheral nerve is transected, a bulbous swelling, or neuroma, will develop at the severed end of the nerve (Figure 4.1). Neuromas consist of disorganized, chaotic axons encased in significant scar and fibrous tissue. They are frequently sensitive to pressure and other forms of mechanical irritation, causing a focal pain that is often difficult to treat. By providing a distal muscle target for the proximal transected axons to grow into, targeted muscle reinnervation (TMR) may represent a novel technique for the prevention and treatment of neuromas. In this chapter, we will discuss the pathophysiology.

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Targeted Muscle Reinnervation as a Strategy for Neuroma Prevention

Abstract

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