Targeted muscle reinnervation in above knee amputation: surgical technique

Michael J. Boctor*, Julian L. Klosowiak, Simon Moradian, Iulianna Taritsa, Gregory A. Dumanian, Jason H. Ko

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


In the United States, an estimated 185,000 individuals undergo amputation of their upper or lower limb. This results in residual limb pain in up to 85% of cases. Targeted muscle reinnervation (TMR) is a technique that has been shown to prevent symptomatic neuroma formation. In this video, the authors demonstrate their technique utilizing TMR at the time of above-the-knee amputation. Coaptations are made to provide motor targets for branches of the saphenous, tibial, and peroneal sensory nerves. At the featured patient’s most recent follow-up visit 3 months postoperatively, she reported no stump pain or phantom limb pain.

Original languageEnglish (US)
JournalNeurosurgical Focus: Video
Issue number1
StatePublished - Jan 2023


  • above-the-knee amputation
  • surgical technique
  • targeted muscle reinnervation

ASJC Scopus subject areas

  • Surgery
  • Neurology


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