Targeted nanoscale therapeutics for myocardial infarction

Holly L. Sullivan; Nathan C. Gianneschi; Karen L. Christman

doi:10.1039/d0bm01677b

Targeted nanoscale therapeutics for myocardial infarction

Holly L. Sullivan, Nathan C. Gianneschi, Karen L. Christman^*

^*Corresponding author for this work

Chemistry

Research output: Contribution to journal › Review article › peer-review

10 Scopus citations

Abstract

Nanoscale therapeutics have promise for the administration of therapeutic small molecules and biologics to the heart following myocardial infarction. Directed delivery to the infarcted region of the heart using minimally invasive routes is critical to this promise. In this review, we will discuss the advances and design considerations for two nanoscale therapeutics engineered to target the infarcted heart, nanoparticles and adeno-Associated viruses.

Original language	English (US)
Pages (from-to)	1204-1216
Number of pages	13
Journal	Biomaterials Science
Volume	9
Issue number	4
DOIs	https://doi.org/10.1039/d0bm01677b
State	Published - Feb 21 2021

ASJC Scopus subject areas

Biomedical Engineering
General Materials Science

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10.1039/d0bm01677b

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title = "Targeted nanoscale therapeutics for myocardial infarction",

abstract = "Nanoscale therapeutics have promise for the administration of therapeutic small molecules and biologics to the heart following myocardial infarction. Directed delivery to the infarcted region of the heart using minimally invasive routes is critical to this promise. In this review, we will discuss the advances and design considerations for two nanoscale therapeutics engineered to target the infarcted heart, nanoparticles and adeno-Associated viruses.",

author = "Sullivan, {Holly L.} and Gianneschi, {Nathan C.} and Christman, {Karen L.}",

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AU - Sullivan, Holly L.

AU - Gianneschi, Nathan C.

AU - Christman, Karen L.

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PY - 2021/2/21

Y1 - 2021/2/21

N2 - Nanoscale therapeutics have promise for the administration of therapeutic small molecules and biologics to the heart following myocardial infarction. Directed delivery to the infarcted region of the heart using minimally invasive routes is critical to this promise. In this review, we will discuss the advances and design considerations for two nanoscale therapeutics engineered to target the infarcted heart, nanoparticles and adeno-Associated viruses.

AB - Nanoscale therapeutics have promise for the administration of therapeutic small molecules and biologics to the heart following myocardial infarction. Directed delivery to the infarcted region of the heart using minimally invasive routes is critical to this promise. In this review, we will discuss the advances and design considerations for two nanoscale therapeutics engineered to target the infarcted heart, nanoparticles and adeno-Associated viruses.

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Targeted nanoscale therapeutics for myocardial infarction

Abstract

ASJC Scopus subject areas

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