Targeting EEG/LFP synchrony with neural nets

Yitong Li, Michael Andrew Murias, Samantha Major, Geraldine Dawson, Kafui Dzirasa, Lawrence Carin, David E. Carlson

    Research output: Contribution to journalConference articlepeer-review

    4 Scopus citations

    Abstract

    We consider the analysis of Electroencephalography (EEG) and Local Field Potential (LFP) datasets, which are "big" in terms of the size of recorded data but rarely have sufficient labels required to train complex models (e.g., conventional deep learning methods). Furthermore, in many scientific applications, the goal is to be able to understand the underlying features related to the classification, which prohibits the blind application of deep networks. This motivates the development of a new model based on parameterized convolutional filters guided by previous neuroscience research; the filters learn relevant frequency bands while targeting synchrony, which are frequency-specific power and phase correlations between electrodes. This results in a highly expressive convolutional neural network with only a few hundred parameters, applicable to smaller datasets. The proposed approach is demonstrated to yield competitive (often state-of-the-art) predictive performance during our empirical tests while yielding interpretable features. Furthermore, a Gaussian process adapter is developed to combine analysis over distinct electrode layouts, allowing the joint processing of multiple datasets to address overfitting and improve generalizability. Finally, it is demonstrated that the proposed framework effectively tracks neural dynamics on children in a clinical trial on Autism Spectrum Disorder.

    Original languageEnglish (US)
    Pages (from-to)4621-4631
    Number of pages11
    JournalAdvances in Neural Information Processing Systems
    Volume2017-December
    StatePublished - Jan 1 2017
    Event31st Annual Conference on Neural Information Processing Systems, NIPS 2017 - Long Beach, United States
    Duration: Dec 4 2017Dec 9 2017

    ASJC Scopus subject areas

    • Computer Networks and Communications
    • Information Systems
    • Signal Processing

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