Task-Dependent Changes in the Large-Scale Dynamics and Necessity of Cortical Regions

Lucas Pinto, Kanaka Rajan, Brian DePasquale, Stephan Y. Thiberge, David W. Tank*, Carlos D. Brody

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

31 Scopus citations


Pinto et al. show that more complex perceptual decisions engage more diverse and spatially distributed computations across the cortex than simpler decisions, even when sensory stimuli and motor output are held constant.

Original languageEnglish (US)
Pages (from-to)810-824.e9
Issue number4
StatePublished - Nov 20 2019
Externally publishedYes


  • cortex
  • decision making
  • evidence accumulation
  • mouse behavior
  • optogenetics
  • RNN
  • virtual reality
  • widefield Ca imaging
  • working memory

ASJC Scopus subject areas

  • Neuroscience(all)

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