TY - JOUR
T1 - Technical aspects of endobronchial ultrasound-guided transbronchial needle aspiration CHEST guideline and expert panel report
AU - Wahidi, Momen M.
AU - Herth, Felix
AU - Yasufuku, Kazuhiro
AU - Shepherd, Ray Wesley
AU - Yarmus, Lonny
AU - Chawla, Mohit
AU - Lamb, Carla
AU - Casey, Kenneth R.
AU - Patel, Sheena
AU - Silvestri, Gerard A.
AU - Feller-Kopman, David J.
N1 - Funding Information:
FUNDING/SUPPORT: This study was funded in total by internal funds from the American College of Chest Physicians.
Publisher Copyright:
© 2016 American College of Chest Physicians. Published by Elsevier Inc. All rights reserved.
PY - 2016/3
Y1 - 2016/3
N2 - BACKGROUND: Endobronchial ultrasound (EBUS) was introduced in the last decade, enabling real-time guidance of transbronchial needle aspiration (TBNA) of mediastinal and hilar structures and parabronchial lungmasses. Themany publications produced about EBUS-TBNA have led to a better understanding of the performance characteristics of this procedure. The goal of this document was to examine the current literature on the technical aspects of EBUS-TBNA as they relate to patient, technology, and proceduralist factors to provide evidence-based and expert guidance to clinicians. METHODS: Rigorous methodology has been applied to provide a trustworthy evidence-based guideline and expert panel report. A group of approved panelists developed key clinical questions by using the PICO (population, intervention, comparator, and outcome) format that addressed specific topics on the technical aspects of EBUS-TBNA. MEDLINE (via PubMed) and the Cochrane Library were systematically searched for relevant literature, which was supplemented by manual searches. References were screened for inclusion, and well-recognized document evaluation tools were used to assess the quality of included studies, to extract meaningful data, and to grade the level of evidence to support each recommendation or suggestion. RESULTS: Our systematic review and critical analysis of the literature on 15 PICO questions related to the technical aspects of EBUS-TBNA resulted in 12 statements: 7 evidence-based graded recommendations and 5 ungraded consensus-based statements. Three questions did not have sufficient evidence to generate a statement. CONCLUSIONS: Evidence on the technical aspects of EBUS-TBNA varies in strength but is satisfactory in certain areas to guide clinicians on the best conditions to perform EBUSguided tissue sampling. Additional research is needed to enhance our knowledge regarding the optimal performance of this effective procedure.
AB - BACKGROUND: Endobronchial ultrasound (EBUS) was introduced in the last decade, enabling real-time guidance of transbronchial needle aspiration (TBNA) of mediastinal and hilar structures and parabronchial lungmasses. Themany publications produced about EBUS-TBNA have led to a better understanding of the performance characteristics of this procedure. The goal of this document was to examine the current literature on the technical aspects of EBUS-TBNA as they relate to patient, technology, and proceduralist factors to provide evidence-based and expert guidance to clinicians. METHODS: Rigorous methodology has been applied to provide a trustworthy evidence-based guideline and expert panel report. A group of approved panelists developed key clinical questions by using the PICO (population, intervention, comparator, and outcome) format that addressed specific topics on the technical aspects of EBUS-TBNA. MEDLINE (via PubMed) and the Cochrane Library were systematically searched for relevant literature, which was supplemented by manual searches. References were screened for inclusion, and well-recognized document evaluation tools were used to assess the quality of included studies, to extract meaningful data, and to grade the level of evidence to support each recommendation or suggestion. RESULTS: Our systematic review and critical analysis of the literature on 15 PICO questions related to the technical aspects of EBUS-TBNA resulted in 12 statements: 7 evidence-based graded recommendations and 5 ungraded consensus-based statements. Three questions did not have sufficient evidence to generate a statement. CONCLUSIONS: Evidence on the technical aspects of EBUS-TBNA varies in strength but is satisfactory in certain areas to guide clinicians on the best conditions to perform EBUSguided tissue sampling. Additional research is needed to enhance our knowledge regarding the optimal performance of this effective procedure.
KW - Endobronchial ultrasound
KW - Evidence-based medicine
KW - Guidelines
KW - Transbronchial needle aspiration
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U2 - 10.1378/chest.15-1216
DO - 10.1378/chest.15-1216
M3 - Article
C2 - 26402427
AN - SCOPUS:84960358508
SN - 0012-3692
VL - 149
SP - 816
EP - 835
JO - CHEST
JF - CHEST
IS - 3
ER -