Technical Aspects of Radioembolization with 90Y Microspheres

Riad Salem*, Robert J Lewandowski, Kent T Sato, Bassel Atassi, Robert K. Ryu, Saad Ibrahim, Albert A Nemcek Jr, Reed A. Omary, David C. Madoff, Ravi Murthy

*Corresponding author for this work

Research output: Contribution to journalArticle

83 Citations (Scopus)

Abstract

Embolotherapy with radioactive microspheres, radioembolization, is gaining clinical acceptance as a therapeutic option for patients with liver malignancies. Knowledge of the anatomic variants in the mesenteric system is critical to safely administer this therapy. The purpose of this review is to provide a thorough discussion and detailed presentation of the technical aspects of radioembolization specifically as it pertains to the implantation devices. Normal vascular anatomy, commonly encountered variants, and factors involved in changes to regional perfusion in the presence of liver tumors are discussed. In addition, the basic principles described in this manuscript apply to all liver-directed transarterial therapies, such as chemoembolization and/or drug-eluting microspheres.

Original languageEnglish (US)
Pages (from-to)12-29
Number of pages18
JournalTechniques in Vascular and Interventional Radiology
Volume10
Issue number1
DOIs
StatePublished - Mar 1 2007

Fingerprint

Microspheres
Liver
Therapeutic Embolization
Blood Vessels
Neoplasms
Anatomy
Therapeutics
Perfusion
Equipment and Supplies
Pharmaceutical Preparations

Keywords

  • SIR-Spheres
  • TheraSphere
  • Yttrium-90
  • brachytherapy
  • embolization
  • liver cancer
  • radioembolization
  • radiotherapy

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

Cite this

Salem, Riad ; Lewandowski, Robert J ; Sato, Kent T ; Atassi, Bassel ; Ryu, Robert K. ; Ibrahim, Saad ; Nemcek Jr, Albert A ; Omary, Reed A. ; Madoff, David C. ; Murthy, Ravi. / Technical Aspects of Radioembolization with 90Y Microspheres. In: Techniques in Vascular and Interventional Radiology. 2007 ; Vol. 10, No. 1. pp. 12-29.
@article{676b7431aa044fad99742c8520754471,
title = "Technical Aspects of Radioembolization with 90Y Microspheres",
abstract = "Embolotherapy with radioactive microspheres, radioembolization, is gaining clinical acceptance as a therapeutic option for patients with liver malignancies. Knowledge of the anatomic variants in the mesenteric system is critical to safely administer this therapy. The purpose of this review is to provide a thorough discussion and detailed presentation of the technical aspects of radioembolization specifically as it pertains to the implantation devices. Normal vascular anatomy, commonly encountered variants, and factors involved in changes to regional perfusion in the presence of liver tumors are discussed. In addition, the basic principles described in this manuscript apply to all liver-directed transarterial therapies, such as chemoembolization and/or drug-eluting microspheres.",
keywords = "SIR-Spheres, TheraSphere, Yttrium-90, brachytherapy, embolization, liver cancer, radioembolization, radiotherapy",
author = "Riad Salem and Lewandowski, {Robert J} and Sato, {Kent T} and Bassel Atassi and Ryu, {Robert K.} and Saad Ibrahim and {Nemcek Jr}, {Albert A} and Omary, {Reed A.} and Madoff, {David C.} and Ravi Murthy",
year = "2007",
month = "3",
day = "1",
doi = "10.1053/j.tvir.2007.08.001",
language = "English (US)",
volume = "10",
pages = "12--29",
journal = "Techniques in Vascular and Interventional Radiology",
issn = "1089-2516",
publisher = "W.B. Saunders Ltd",
number = "1",

}

Technical Aspects of Radioembolization with 90Y Microspheres. / Salem, Riad; Lewandowski, Robert J; Sato, Kent T; Atassi, Bassel; Ryu, Robert K.; Ibrahim, Saad; Nemcek Jr, Albert A; Omary, Reed A.; Madoff, David C.; Murthy, Ravi.

In: Techniques in Vascular and Interventional Radiology, Vol. 10, No. 1, 01.03.2007, p. 12-29.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Technical Aspects of Radioembolization with 90Y Microspheres

AU - Salem, Riad

AU - Lewandowski, Robert J

AU - Sato, Kent T

AU - Atassi, Bassel

AU - Ryu, Robert K.

AU - Ibrahim, Saad

AU - Nemcek Jr, Albert A

AU - Omary, Reed A.

AU - Madoff, David C.

AU - Murthy, Ravi

PY - 2007/3/1

Y1 - 2007/3/1

N2 - Embolotherapy with radioactive microspheres, radioembolization, is gaining clinical acceptance as a therapeutic option for patients with liver malignancies. Knowledge of the anatomic variants in the mesenteric system is critical to safely administer this therapy. The purpose of this review is to provide a thorough discussion and detailed presentation of the technical aspects of radioembolization specifically as it pertains to the implantation devices. Normal vascular anatomy, commonly encountered variants, and factors involved in changes to regional perfusion in the presence of liver tumors are discussed. In addition, the basic principles described in this manuscript apply to all liver-directed transarterial therapies, such as chemoembolization and/or drug-eluting microspheres.

AB - Embolotherapy with radioactive microspheres, radioembolization, is gaining clinical acceptance as a therapeutic option for patients with liver malignancies. Knowledge of the anatomic variants in the mesenteric system is critical to safely administer this therapy. The purpose of this review is to provide a thorough discussion and detailed presentation of the technical aspects of radioembolization specifically as it pertains to the implantation devices. Normal vascular anatomy, commonly encountered variants, and factors involved in changes to regional perfusion in the presence of liver tumors are discussed. In addition, the basic principles described in this manuscript apply to all liver-directed transarterial therapies, such as chemoembolization and/or drug-eluting microspheres.

KW - SIR-Spheres

KW - TheraSphere

KW - Yttrium-90

KW - brachytherapy

KW - embolization

KW - liver cancer

KW - radioembolization

KW - radiotherapy

UR - http://www.scopus.com/inward/record.url?scp=35548988343&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=35548988343&partnerID=8YFLogxK

U2 - 10.1053/j.tvir.2007.08.001

DO - 10.1053/j.tvir.2007.08.001

M3 - Article

C2 - 17980315

AN - SCOPUS:35548988343

VL - 10

SP - 12

EP - 29

JO - Techniques in Vascular and Interventional Radiology

JF - Techniques in Vascular and Interventional Radiology

SN - 1089-2516

IS - 1

ER -