Telephone-administered cognitive-behavioral therapy for the treatment of depressive symptoms in multiple sclerosis

David C. Mohr*, William Likosky, Andrew Bertagnolli, Donald E. Goodkin, Judy Van Der Wende, Pat Dwyer, Leah P. Dick

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

190 Scopus citations

Abstract

This study examined the efficacy of an 8-week telephone-administered cognitive-behavioral therapy for the treatment of depressive symptomatology in multiple sclerosis (MS) patients. The treatment Coping with MS (CMS) included a patient workbook designed to structure the treatment, provide visual aids, and help with homework assignments. Thirty-two patients with MS, who scored at least 15 on the Profile of Mood States Depression-Dejection scale, were randomly assigned to either the telephone CMS or to a usual-care control (UCC) condition. Depressive symptomatology decreased significantly in the CMS condition compared with the UCC condition. Furthermore, adherence to interferon beta-1a, a disease-modifying medication for the treatment of MS, was significantly better at the 4-month follow-up among patients who received CMS as compared with those in the UCC condition.

Original languageEnglish (US)
Pages (from-to)356-361
Number of pages6
JournalJournal of Consulting and Clinical Psychology
Volume68
Issue number2
DOIs
StatePublished - Jan 1 2000

ASJC Scopus subject areas

  • Clinical Psychology
  • Psychiatry and Mental health

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