Temperature controlled grafted polymer network incorporated with magnetic nano particles to control drug release induced by an external magnetothermal trigger

Induvadana Ankareddi; Mary L. Hampel; Mary Kathryn Sewell; Dong Hyun Kim; Christopher S. Brazel

Temperature controlled grafted polymer network incorporated with magnetic nano particles to control drug release induced by an external magnetothermal trigger

Induvadana Ankareddi, Mary L. Hampel, Mary Kathryn Sewell, Dong Hyun Kim, Christopher S. Brazel^*

^*Corresponding author for this work

Radiology

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

5 Scopus citations

Abstract

A thermosensitive grafted polymeric system which can be triggered to release the loaded drug with an increase in temperature, induced by a magnetic thermal heating event was developed. The desirable carrier will have minimal release at 37°C so that the system can be localized (e.g., to cancer cells) prior to activation of the delivery of medication. The grafted hydrogel system is shown to exhibit a desirable positive thermal response with an increased drug diffusion coefficient for temperatures higher than physiological temperature.

Original language	English (US)
Title of host publication	2007 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2007, Technical Proceedings
Pages	431-434
Number of pages	4
State	Published - 2007
Event	2007 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2007 - Santa Clara, CA, United States Duration: May 20 2007 → May 24 2007

Publication series

Name	2007 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2007, Technical Proceedings
Volume	2

Other

Other	2007 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2007
Country/Territory	United States
City	Santa Clara, CA
Period	5/20/07 → 5/24/07

Keywords

Grafted
Hydrogel
Thermosensitive

ASJC Scopus subject areas

Mechanical Engineering

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Cite this

Ankareddi, I., Hampel, M. L., Sewell, M. K., Kim, D. H., & Brazel, C. S. (2007). Temperature controlled grafted polymer network incorporated with magnetic nano particles to control drug release induced by an external magnetothermal trigger. In 2007 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2007, Technical Proceedings (pp. 431-434). (2007 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2007, Technical Proceedings; Vol. 2).

Ankareddi, Induvadana ; Hampel, Mary L. ; Sewell, Mary Kathryn et al. / Temperature controlled grafted polymer network incorporated with magnetic nano particles to control drug release induced by an external magnetothermal trigger. 2007 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2007, Technical Proceedings. 2007. pp. 431-434 (2007 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2007, Technical Proceedings).

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title = "Temperature controlled grafted polymer network incorporated with magnetic nano particles to control drug release induced by an external magnetothermal trigger",

abstract = "A thermosensitive grafted polymeric system which can be triggered to release the loaded drug with an increase in temperature, induced by a magnetic thermal heating event was developed. The desirable carrier will have minimal release at 37°C so that the system can be localized (e.g., to cancer cells) prior to activation of the delivery of medication. The grafted hydrogel system is shown to exhibit a desirable positive thermal response with an increased drug diffusion coefficient for temperatures higher than physiological temperature.",

keywords = "Grafted, Hydrogel, Thermosensitive",

author = "Induvadana Ankareddi and Hampel, {Mary L.} and Sewell, {Mary Kathryn} and Kim, {Dong Hyun} and Brazel, {Christopher S.}",

year = "2007",

language = "English (US)",

isbn = "1420063421",

series = "2007 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2007, Technical Proceedings",

pages = "431--434",

booktitle = "2007 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2007, Technical Proceedings",

note = "2007 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2007 ; Conference date: 20-05-2007 Through 24-05-2007",

}

Ankareddi, I, Hampel, ML, Sewell, MK, Kim, DH & Brazel, CS 2007, Temperature controlled grafted polymer network incorporated with magnetic nano particles to control drug release induced by an external magnetothermal trigger. in 2007 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2007, Technical Proceedings. 2007 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2007, Technical Proceedings, vol. 2, pp. 431-434, 2007 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2007, Santa Clara, CA, United States, 5/20/07.

Temperature controlled grafted polymer network incorporated with magnetic nano particles to control drug release induced by an external magnetothermal trigger. / Ankareddi, Induvadana; Hampel, Mary L.; Sewell, Mary Kathryn et al.

2007 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2007, Technical Proceedings. 2007. p. 431-434 (2007 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2007, Technical Proceedings; Vol. 2).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

TY - GEN

T1 - Temperature controlled grafted polymer network incorporated with magnetic nano particles to control drug release induced by an external magnetothermal trigger

AU - Ankareddi, Induvadana

AU - Hampel, Mary L.

AU - Sewell, Mary Kathryn

AU - Kim, Dong Hyun

AU - Brazel, Christopher S.

PY - 2007

Y1 - 2007

N2 - A thermosensitive grafted polymeric system which can be triggered to release the loaded drug with an increase in temperature, induced by a magnetic thermal heating event was developed. The desirable carrier will have minimal release at 37°C so that the system can be localized (e.g., to cancer cells) prior to activation of the delivery of medication. The grafted hydrogel system is shown to exhibit a desirable positive thermal response with an increased drug diffusion coefficient for temperatures higher than physiological temperature.

AB - A thermosensitive grafted polymeric system which can be triggered to release the loaded drug with an increase in temperature, induced by a magnetic thermal heating event was developed. The desirable carrier will have minimal release at 37°C so that the system can be localized (e.g., to cancer cells) prior to activation of the delivery of medication. The grafted hydrogel system is shown to exhibit a desirable positive thermal response with an increased drug diffusion coefficient for temperatures higher than physiological temperature.

KW - Grafted

KW - Hydrogel

KW - Thermosensitive

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M3 - Conference contribution

AN - SCOPUS:34547992766

SN - 1420063421

SN - 9781420063424

SN - 1420061836

SN - 9781420061833

T3 - 2007 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2007, Technical Proceedings

SP - 431

EP - 434

BT - 2007 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2007, Technical Proceedings

T2 - 2007 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2007

Y2 - 20 May 2007 through 24 May 2007

ER -

Ankareddi I, Hampel ML, Sewell MK, Kim DH, Brazel CS. Temperature controlled grafted polymer network incorporated with magnetic nano particles to control drug release induced by an external magnetothermal trigger. In 2007 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2007, Technical Proceedings. 2007. p. 431-434. (2007 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2007, Technical Proceedings).

Temperature controlled grafted polymer network incorporated with magnetic nano particles to control drug release induced by an external magnetothermal trigger

Abstract

Publication series

Other

Keywords

ASJC Scopus subject areas

UN SDGs

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