Template-directed syntheses of rigid oligorotaxanes under thermodynamic control

Matthew E. Belowich, Cory Valente, J Fraser Stoddart

Research output: Contribution to journalArticlepeer-review

44 Scopus citations


Strategically placing secondary dialkyl-ammonium recognition sites at the magic distance of 3.5 Å apart in the dumbbell components of a series of oligorotaxanes (see picture) renders otherwise conformationally floppy [n]rotaxanes rigid and rodlike. These oligorotaxanes form with near-quantitative conversion under thermodynamic control using dynamic covalent chemistry.

Original languageEnglish (US)
Pages (from-to)7208-7212
Number of pages5
JournalAngewandte Chemie - International Edition
Issue number40
StatePublished - Sep 24 2010


  • Dynamic covalent chemistry
  • Mechanically interlocked molecules
  • Molecular recognition
  • Noncovalent bonding interactions
  • Self-assembly

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)

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