Testicular juvenile granulosa cell tumor in a newborn: Case report and review of the literature

Borislav A. Alexiev; Samuel M. Alaish; Chen Chih Sun

doi:10.1177/1066896907302423

Testicular juvenile granulosa cell tumor in a newborn: Case report and review of the literature

Borislav A. Alexiev^*, Samuel M. Alaish, Chen Chih Sun

^*Corresponding author for this work

Pathology

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Abstract

Juvenile granulosa cell tumor of the testis of neonates and infants is an uncommon lesion frequently associated with abnormal sex chromosome and ambiguous genitalia. This report describes a juvenile granulosa cell tumor arising in the testis of a neonate. Chromosome analysis of the tumor showed a normal male karyotype 46 XY. Histopathology and immunohistochemical studies revealed the occurrence of 2 well-differentiated epithelial-like and smooth muscle-like components in the neoplasm. The morphologic clues leading to the correct diagnosis of juvenile granulosa cell tumor and the possible histogenesis are briefly discussed.

Original language	English (US)
Pages (from-to)	321-325
Number of pages	5
Journal	International Journal of Surgical Pathology
Volume	15
Issue number	3
DOIs	https://doi.org/10.1177/1066896907302423
State	Published - Jul 2007

Keywords

Juvenile granulosae cell tumor
Neonate
Testis

ASJC Scopus subject areas

Anatomy
Surgery
Pathology and Forensic Medicine

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10.1177/1066896907302423

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abstract = "Juvenile granulosa cell tumor of the testis of neonates and infants is an uncommon lesion frequently associated with abnormal sex chromosome and ambiguous genitalia. This report describes a juvenile granulosa cell tumor arising in the testis of a neonate. Chromosome analysis of the tumor showed a normal male karyotype 46 XY. Histopathology and immunohistochemical studies revealed the occurrence of 2 well-differentiated epithelial-like and smooth muscle-like components in the neoplasm. The morphologic clues leading to the correct diagnosis of juvenile granulosa cell tumor and the possible histogenesis are briefly discussed.",

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year = "2007",

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AU - Alaish, Samuel M.

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AB - Juvenile granulosa cell tumor of the testis of neonates and infants is an uncommon lesion frequently associated with abnormal sex chromosome and ambiguous genitalia. This report describes a juvenile granulosa cell tumor arising in the testis of a neonate. Chromosome analysis of the tumor showed a normal male karyotype 46 XY. Histopathology and immunohistochemical studies revealed the occurrence of 2 well-differentiated epithelial-like and smooth muscle-like components in the neoplasm. The morphologic clues leading to the correct diagnosis of juvenile granulosa cell tumor and the possible histogenesis are briefly discussed.

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Testicular juvenile granulosa cell tumor in a newborn: Case report and review of the literature

Abstract

Keywords

ASJC Scopus subject areas

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