Testing a hierarchical model of neuroticism and its cognitive facets: Latent structure and prospective prediction of first onsets of anxiety and unipolar mood disorders during 3 years in late adolescence

Richard E Zinbarg*, Susan Mineka, Lyuba Bobova, Michelle G. Craske, Suzanne Vrshek-Schallhorn, James W Griffith, Kate Wolitzky-Taylor, Allison M. Waters, Jennifer A. Sumner, Deepika Anand

*Corresponding author for this work

Research output: Contribution to journalArticle

38 Scopus citations

Abstract

Neuroticism and several other traits have been proposed to confer vulnerability for unipolar mood disorders (UMDs) and anxiety disorders (ADs). However, it is unclear whether the associations of these vulnerabilities with these disorders are attributable to a latent variable common to all vulnerabilities, more narrow latent variables, or both. In addition, some researchers have suggested that neuroticism predicts UMDs, ADs, and substance use disorders (SUDs) with comparable strength, whereas other researchers have hypothesized that neuroticism is more strongly related to UMDs and ADs. We tested hypotheses about the factor structure of several vulnerabilities and the prospective associations of these latent variables with initial onsets of UMDs, ADs, and SUDs during a 3-year period in 547 participants recruited as high school juniors. Although a general neuroticism factor predicted SUDs, it predicted UMDs and ADs more strongly and especially predicted comorbid UMDs and ADs. There was also mixed support for specific associations involving more narrow latent vulnerabilities.

Original languageEnglish (US)
Pages (from-to)805-824
Number of pages20
JournalClinical Psychological Science
Volume4
Issue number5
DOIs
StatePublished - Jan 1 2016

Keywords

  • Anxiety disorders
  • Cognitive vulnerability
  • Mood disorders
  • Neuroticism
  • Substance use disorders

ASJC Scopus subject areas

  • Clinical Psychology

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