Testing deceased organ donors for infections: An organ procurement organization survey

Nicole M. Theodoropoulos*, Melissa A. Greenwald, Peter Chin-Hong, Michael G. Ison

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Organ procurement organizations (OPO) test potential deceased organ donors for infectious diseases required by policy, but many also perform testing for additional infections. The current state of donor testing in the United States is unknown. We sent an IRB approved survey to all 57 U.S. OPOs using REDCap. Descriptive statistics were performed. From the 57 OPOs, we received 46 (80.7%) unique responses with all 11 United Network of Organ Sharing regions represented. Forty of 46 (87%) OPO respondents consulted an Infectious Diseases physician when needed. Eighteen of 46 (39%) tested for West Nile virus (WNV) and 17 of 18 (94%) tested year-round. Eleven of 46 (23.9%) tested for Strongyloides infection while 17 of 46 (37%) tested for Chagas disease. All OPOs performed prospective nucleic acid testing (NAT) for HIV, hepatitis B and hepatitis C on all donors. OPO testing of additional infections has increased since prior surveys but remains variable. Standardization of organ donor infectious diseases evaluation should be considered.

Original languageEnglish (US)
Pages (from-to)1924-1930
Number of pages7
JournalAmerican Journal of Transplantation
Volume21
Issue number5
DOIs
StatePublished - May 2021

Keywords

  • clinical research/practice
  • donors and donation: deceased
  • donors and donation: donor evaluation
  • donors and donation: donor-derived infections
  • infectious disease

ASJC Scopus subject areas

  • Immunology and Allergy
  • Transplantation
  • Pharmacology (medical)

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