Testosterone Use in the Perioperative Setting

Bailey N. Goyette, Matthew T. Hudnall, Joshua A. Halpern*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review


Purpose of Review: The number of men on testosterone replacement therapy (TRT) has increased dramatically in recent years. Given the potential cardiovascular risks of TRT, there has been some concern that TRT use in the perioperative setting may potentiate the inherent cardiovascular risks ofanesthesia and surgical intervention. Conversely, a large proportion of men with low testosterone remain undiagnosed or untreated Recent Findings: There are numerous benefits to TRT use in the appropriate candidate, many of which may be uniquely advantageous in the perioperative setting. Here we review of the most recent literature to examine the risks and benefits of TRT in the perioperative setting. Summary: While studies are limited, available evidence does not suggest an increased risk of perioperative cardiovascular complications among patients using TRT, and there are small, single-center studies indicating a beneficial role for TRT use in specific surgical contexts. Further studies are needed to better delineate the unique risks and benefits of TRT in the perioperative setting.

Original languageEnglish (US)
Pages (from-to)1-8
Number of pages8
JournalCurrent Sexual Health Reports
Issue number1
StatePublished - Mar 2022


  • Cardiovascular risk
  • Hypogonadism
  • Low testosterone

ASJC Scopus subject areas

  • Obstetrics and Gynecology
  • Urology


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