TGFBR1*6A is not associated with prostate cancer in men of European ancestry

B. K. Suarez*, P. Pal, C. H. Jin, R. Kaushal, G. Sun, L. Jin, B. Pasche, R. Deka, W. J. Catalona

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

The TGFBR1*6A (*6A) variant in exon 1 of the TGFBR1 gene has been postulated as a putative tumor susceptibility allele in several studies. We have performed a case -control study in 537 men with histologically verified prostate cancer and in 488 unrelated controls to investigate the association of *6A with prostate cancer. Our results revealed that the frequency of the *6A allele does not differ in men with prostate cancer compared to healthy controls, even in a subset of age-matched cases and controls. There is no compelling evidence for an association of the *6A variant with prostate cancer.

Original languageEnglish (US)
Pages (from-to)50-53
Number of pages4
JournalProstate Cancer and Prostatic Diseases
Volume8
Issue number1
DOIs
StatePublished - Mar 2005

Keywords

  • Association
  • TGFBR1

ASJC Scopus subject areas

  • Oncology
  • Urology
  • Cancer Research

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