Thalamic visual prosthesis

Hieu T. Nguyen, Siva M. Tangutooru, Corey M. Rountree, Andrew J.Kantzos Kantzos, Faris Tarlochan, W. Jong Yoon, John B. Troy*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

Glaucoma is a neurological disorder leading to blindness initially through the loss of retinal ganglion cells, followed by loss of neurons higher in the visual system. Some work has been undertaken to develop prostheses for glaucoma patients targeting tissues along the visual pathway, including the lateral geniculate nucleus (LGN) of the thalamus, but especially the visual cortex. This review makes the case for a visual prosthesis that targets the LGN. The compact nature and orderly structure of this nucleus make it a potentially better target to restore vision than the visual cortex. Existing research for the development of a thalamic visual prosthesis will be discussed along with the gaps that need to be addressed before such a technology could be applied clinically, as well as the challenge posed by the loss of LGN neurons as glaucoma progresses.

Original languageEnglish (US)
Article number7470249
Pages (from-to)1573-1580
Number of pages8
JournalIEEE Transactions on Biomedical Engineering
Volume63
Issue number8
DOIs
StatePublished - Aug 2016

Keywords

  • Electrical stimulation
  • glaucoma
  • lateral geniculate nucleus (LGN)
  • thalamic visual prosthesis
  • vision repair

ASJC Scopus subject areas

  • Biomedical Engineering

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