Thalassemias

Alissa Martin; Alexis A. Thompson

doi:10.1016/j.pcl.2013.08.008

Thalassemias

Alissa Martin, Alexis A. Thompson^*

^*Corresponding author for this work

Pediatrics

Research output: Contribution to journal › Review article › peer-review

80 Scopus citations

Abstract

The thalassemia syndromes are hemoglobin disorders that result from significantly reduced or absent synthesis of either the α- or β-globin chains. The result is a chronic hemolytic anemia with ineffective erythropoiesis and bone marrow overstimulation. This article reviews current diagnostic approaches, complications, and disease management of thalassemia.

Original language	English (US)
Pages (from-to)	1383-1391
Number of pages	9
Journal	Pediatric Clinics of North America
Volume	60
Issue number	6
DOIs	https://doi.org/10.1016/j.pcl.2013.08.008
State	Published - Dec 2013

Keywords

Anemia
Hemoglobinopathies
Iron overload
Thalassemia

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health

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10.1016/j.pcl.2013.08.008

Cite this

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title = "Thalassemias",

abstract = "The thalassemia syndromes are hemoglobin disorders that result from significantly reduced or absent synthesis of either the α- or β-globin chains. The result is a chronic hemolytic anemia with ineffective erythropoiesis and bone marrow overstimulation. This article reviews current diagnostic approaches, complications, and disease management of thalassemia.",

keywords = "Anemia, Hemoglobinopathies, Iron overload, Thalassemia",

author = "Alissa Martin and Thompson, {Alexis A.}",

year = "2013",

month = dec,

doi = "10.1016/j.pcl.2013.08.008",

language = "English (US)",

volume = "60",

pages = "1383--1391",

journal = "Pediatric Clinics of North America",

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AU - Martin, Alissa

AU - Thompson, Alexis A.

PY - 2013/12

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N2 - The thalassemia syndromes are hemoglobin disorders that result from significantly reduced or absent synthesis of either the α- or β-globin chains. The result is a chronic hemolytic anemia with ineffective erythropoiesis and bone marrow overstimulation. This article reviews current diagnostic approaches, complications, and disease management of thalassemia.

AB - The thalassemia syndromes are hemoglobin disorders that result from significantly reduced or absent synthesis of either the α- or β-globin chains. The result is a chronic hemolytic anemia with ineffective erythropoiesis and bone marrow overstimulation. This article reviews current diagnostic approaches, complications, and disease management of thalassemia.

KW - Anemia

KW - Hemoglobinopathies

KW - Iron overload

KW - Thalassemia

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U2 - 10.1016/j.pcl.2013.08.008

DO - 10.1016/j.pcl.2013.08.008

M3 - Review article

C2 - 24237977

AN - SCOPUS:84887608781

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VL - 60

SP - 1383

EP - 1391

JO - Pediatric Clinics of North America

JF - Pediatric Clinics of North America

IS - 6

ER -

Thalassemias

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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