Thalidomide-induced peripheral neuropathy. Effect of serum factor on nerve cultures

I. K. Aronson; R. Yu; D. P. West; H. Van den Broek; J. Antel

doi:10.1001/archderm.120.11.1466

Thalidomide-induced peripheral neuropathy. Effect of serum factor on nerve cultures

I. K. Aronson, R. Yu, D. P. West, H. Van den Broek, J. Antel

Dermatology

Research output: Contribution to journal › Article › peer-review

Abstract

Sensory neuropathies developed in three of four patients with prurigo nodularis who had been treated with thalidomide. The serum samples of the patients who had neuropathy produced morphologic changes in cultured dorsal root ganglion cells. These observed changes support the postulate that thalidomide induces primary neuronal degeneration.

Original language	English (US)
Pages (from-to)	1466-1470
Number of pages	5
Journal	Archives of Dermatology
Volume	120
Issue number	11
DOIs	https://doi.org/10.1001/archderm.120.11.1466
State	Published - Dec 1 1984

ASJC Scopus subject areas

Dermatology

Access to Document

10.1001/archderm.120.11.1466

Cite this

@article{5ea194cf34f2421795523ab3524f23c0,

title = "Thalidomide-induced peripheral neuropathy. Effect of serum factor on nerve cultures",

abstract = "Sensory neuropathies developed in three of four patients with prurigo nodularis who had been treated with thalidomide. The serum samples of the patients who had neuropathy produced morphologic changes in cultured dorsal root ganglion cells. These observed changes support the postulate that thalidomide induces primary neuronal degeneration.",

author = "Aronson, {I. K.} and R. Yu and West, {D. P.} and {Van den Broek}, H. and J. Antel",

year = "1984",

month = dec,

day = "1",

doi = "10.1001/archderm.120.11.1466",

language = "English (US)",

volume = "120",

pages = "1466--1470",

journal = "Archives of Dermatology",

issn = "0003-987X",

publisher = "American Medical Association",

number = "11",

}

TY - JOUR

T1 - Thalidomide-induced peripheral neuropathy. Effect of serum factor on nerve cultures

AU - Aronson, I. K.

AU - Yu, R.

AU - West, D. P.

AU - Van den Broek, H.

AU - Antel, J.

PY - 1984/12/1

Y1 - 1984/12/1

N2 - Sensory neuropathies developed in three of four patients with prurigo nodularis who had been treated with thalidomide. The serum samples of the patients who had neuropathy produced morphologic changes in cultured dorsal root ganglion cells. These observed changes support the postulate that thalidomide induces primary neuronal degeneration.

AB - Sensory neuropathies developed in three of four patients with prurigo nodularis who had been treated with thalidomide. The serum samples of the patients who had neuropathy produced morphologic changes in cultured dorsal root ganglion cells. These observed changes support the postulate that thalidomide induces primary neuronal degeneration.

UR - http://www.scopus.com/inward/record.url?scp=0021690486&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0021690486&partnerID=8YFLogxK

U2 - 10.1001/archderm.120.11.1466

DO - 10.1001/archderm.120.11.1466

M3 - Article

C2 - 6093713

SN - 0003-987X

VL - 120

SP - 1466

EP - 1470

JO - Archives of Dermatology

JF - Archives of Dermatology

IS - 11

ER -

Thalidomide-induced peripheral neuropathy. Effect of serum factor on nerve cultures

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this