Thalidomide-Induced Peripheral Neuropathy: Effect of Serum Factor on Nerve Cultures

Iris K. Aronson*, Riley Yu, Dennis P. West, Hans Van Den Broek, Jack Antel

*Corresponding author for this work

Research output: Contribution to journalArticle

51 Scopus citations

Abstract

• Sensory neuropathies developed in three of four patients with prurigo nodularis who had been treated with thalidomide. The serum samples of the patients who had neuropathy produced morphologic changes in cultured dorsal root ganglion cells. These observed changes support the postulate that thalidomide induces primary neuronal degeneration.

Original languageEnglish (US)
Pages (from-to)1466-1470
Number of pages5
JournalArchives of dermatology
Volume120
Issue number11
DOIs
StatePublished - Jan 1 1984

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ASJC Scopus subject areas

  • Dermatology

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