Thalidomide-Induced Peripheral Neuropathy: Effect of Serum Factor on Nerve Cultures

Iris K. Aronson; Riley Yu; Dennis P. West; Hans Van Den Broek; Jack Antel

doi:10.1001/archderm.1984.01650470072016

Thalidomide-Induced Peripheral Neuropathy: Effect of Serum Factor on Nerve Cultures

Iris K. Aronson^*, Riley Yu, Dennis P. West, Hans Van Den Broek, Jack Antel

^*Corresponding author for this work

Dermatology

Research output: Contribution to journal › Article › peer-review

54 Scopus citations

Abstract

• Sensory neuropathies developed in three of four patients with prurigo nodularis who had been treated with thalidomide. The serum samples of the patients who had neuropathy produced morphologic changes in cultured dorsal root ganglion cells. These observed changes support the postulate that thalidomide induces primary neuronal degeneration.

Original language	English (US)
Pages (from-to)	1466-1470
Number of pages	5
Journal	Archives of Dermatology
Volume	120
Issue number	11
DOIs	https://doi.org/10.1001/archderm.1984.01650470072016
State	Published - Nov 1984

ASJC Scopus subject areas

Dermatology

Access to Document

10.1001/archderm.1984.01650470072016

Cite this

@article{5f498329d5564e309ce793aa7aeeda79,

title = "Thalidomide-Induced Peripheral Neuropathy: Effect of Serum Factor on Nerve Cultures",

abstract = "• Sensory neuropathies developed in three of four patients with prurigo nodularis who had been treated with thalidomide. The serum samples of the patients who had neuropathy produced morphologic changes in cultured dorsal root ganglion cells. These observed changes support the postulate that thalidomide induces primary neuronal degeneration.",

author = "Aronson, {Iris K.} and Riley Yu and West, {Dennis P.} and {Van Den Broek}, Hans and Jack Antel",

year = "1984",

month = nov,

doi = "10.1001/archderm.1984.01650470072016",

language = "English (US)",

volume = "120",

pages = "1466--1470",

journal = "Archives of Dermatology",

issn = "0003-987X",

publisher = "American Medical Association",

number = "11",

}

TY - JOUR

T1 - Thalidomide-Induced Peripheral Neuropathy

T2 - Effect of Serum Factor on Nerve Cultures

AU - Aronson, Iris K.

AU - Yu, Riley

AU - West, Dennis P.

AU - Van Den Broek, Hans

AU - Antel, Jack

PY - 1984/11

Y1 - 1984/11

N2 - • Sensory neuropathies developed in three of four patients with prurigo nodularis who had been treated with thalidomide. The serum samples of the patients who had neuropathy produced morphologic changes in cultured dorsal root ganglion cells. These observed changes support the postulate that thalidomide induces primary neuronal degeneration.

AB - • Sensory neuropathies developed in three of four patients with prurigo nodularis who had been treated with thalidomide. The serum samples of the patients who had neuropathy produced morphologic changes in cultured dorsal root ganglion cells. These observed changes support the postulate that thalidomide induces primary neuronal degeneration.

UR - http://www.scopus.com/inward/record.url?scp=84944969333&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84944969333&partnerID=8YFLogxK

U2 - 10.1001/archderm.1984.01650470072016

DO - 10.1001/archderm.1984.01650470072016

M3 - Article

C2 - 6093713

AN - SCOPUS:84944969333

SN - 0003-987X

VL - 120

SP - 1466

EP - 1470

JO - Archives of Dermatology

JF - Archives of Dermatology

IS - 11

ER -

Thalidomide-Induced Peripheral Neuropathy: Effect of Serum Factor on Nerve Cultures

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this