The 2015 American Thyroid Association guidelines and trends in hemithyroidectomy utilization for pediatric thyroid cancer

Eli Stein, Mehul V. Raval, Inbal Hazkani, Audra Reiter, Jami L. Josefson, Jill H. Samis, Jeffrey C. Rastatter*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

Background: In 2015, the American Thyroid Association (ATA) released its inaugural recommendations for the management of thyroid cancer in children. We aim to evaluate whether there has been a change in hemithyroidectomy utilization for pediatric differentiated thyroid cancer, and the association between those changes and the release of the ATA guidelines. Methods: The National Cancer Database was queried and identified 4776 patients ≤18 years old with differentiated thyroid cancer. Causal impact time-series analysis and logistic analysis were utilized to assess factors associated with use of hemithyroidectomy. Results: Post-2015 hemithyroidectomy rate was greater than predicted based on preguideline trends (predicted: 8.4%, actual: 12.6%, p = 0.001). In logistic analysis of factors associated with hemithyroidectomy use, we find that Papillary histology, tumor size >1 cm, nodal examination, and positive nodes were associated with lower rate of hemithyroidectomy (OR: 0.23, 0.51, 0.62, and 0.18, respectively). Conclusion: There has been a significant increase in hemithyroidectomy utilization for pediatric differentiated thyroid cancer.

Original languageEnglish (US)
Pages (from-to)1833-1841
Number of pages9
JournalHead and Neck
Volume44
Issue number8
DOIs
StatePublished - Aug 2022

Keywords

  • American Thyroid Association
  • NCDB
  • hemithyroidectomy
  • pediatric thyroid cancer
  • thyroidectomy

ASJC Scopus subject areas

  • Otorhinolaryngology

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