TY - JOUR
T1 - The anesthesiologist's role in treating abusive head trauma
AU - Lee, Jennifer K.
AU - Brady, Kenneth Martin
AU - Deutsch, Nina
N1 - Funding Information:
Dr. Lee's work was supported by grants from the National Institutes of Health (NIH) (K08 NS080984) and the American Heart Association. Dr. Lee also has clinical research funding from Medtronic.
Publisher Copyright:
© 2016 International Anesthesia Research Society.
PY - 2016/6/1
Y1 - 2016/6/1
N2 - Abusive head trauma (AHT) is the most common cause of severe traumatic brain injury (TBI) in infants and the leading cause of child abuse-related deaths. For reasons that remain unclear, mortality rates after moderate AHT rival those of severe nonintentional TBI. The vulnerability of the developing brain to injury may be partially responsible for the poor outcomes observed after AHT. AHT is mechanistically more complex than nonintentional TBI. The acute-on-chronic nature of the trauma along with synergistic injury mechanisms that include rapid rotation of the brain, diffuse axonal injury, blunt force trauma, and hypoxia-ischemia make AHT challenging to treat. The anesthesiologist must understand the complex injury mechanisms inherent to AHT, as well as the pediatric TBI treatment guidelines, to decrease the risk of persistent neurologic disability and death. In this review, we discuss the epidemiology of AHT, differences between AHT and nonintentional TBI, the severe pediatric TBI treatment guidelines in the context of AHT, anesthetic considerations, and ethical and legal reporting requirements.
AB - Abusive head trauma (AHT) is the most common cause of severe traumatic brain injury (TBI) in infants and the leading cause of child abuse-related deaths. For reasons that remain unclear, mortality rates after moderate AHT rival those of severe nonintentional TBI. The vulnerability of the developing brain to injury may be partially responsible for the poor outcomes observed after AHT. AHT is mechanistically more complex than nonintentional TBI. The acute-on-chronic nature of the trauma along with synergistic injury mechanisms that include rapid rotation of the brain, diffuse axonal injury, blunt force trauma, and hypoxia-ischemia make AHT challenging to treat. The anesthesiologist must understand the complex injury mechanisms inherent to AHT, as well as the pediatric TBI treatment guidelines, to decrease the risk of persistent neurologic disability and death. In this review, we discuss the epidemiology of AHT, differences between AHT and nonintentional TBI, the severe pediatric TBI treatment guidelines in the context of AHT, anesthetic considerations, and ethical and legal reporting requirements.
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U2 - 10.1213/ANE.0000000000001298
DO - 10.1213/ANE.0000000000001298
M3 - Article
C2 - 27195639
AN - SCOPUS:84969834469
SN - 0003-2999
VL - 122
SP - 1971
EP - 1982
JO - Anesthesia and analgesia
JF - Anesthesia and analgesia
IS - 6
ER -