The angular distribution of directional changes of guided 3T3 cells

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22 Scopus citations


This paper reports that the angular distribution of directional change of 3T3 cells which followed guiding lines on a substrate and left the guidance at various angles shows a peculiar preference of angles between 30° and 60°. Regarding the phenomenon of cellular guidance itself, 3T3 cells faced with a choice between guiding lines toward different directions seem to explore various options before following one. This observation suggests that the outcome of a probing action and not substrate properties alone can explain the guidance behavior of 3T3 cells.

Original languageEnglish (US)
Pages (from-to)53-60
Number of pages8
JournalJournal of Cell Biology
Issue number1
StatePublished - 1979

ASJC Scopus subject areas

  • Cell Biology


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