The Association between Preoperative Frailty and Postoperative Delirium after Cardiac Surgery

Charles H. Brown, Laura Max, Andrew Laflam, Lou Kirk, Alden Gross, Rakesh Arora, Karin Neufeld, Charles W. Hogue*, Jeremy Walston, Aliaksei Pustavoitau

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

54 Scopus citations

Abstract

Delirium is common after cardiac surgery, and preoperative identification of high-risk patients could guide prevention strategies. We prospectively measured frailty in 55 patients before cardiac surgery and assessed postoperative delirium using a validated chart review. The prevalence of frailty was 30.9%. Frail patients had a higher incidence of delirium (47.1%) compared with nonfrail patients (2.6%; P < 0.001). In multivariable models, the relative risk of delirium was ≥2.1-fold greater in frail compared with nonfrail patients (relative risk, 18.3; 95% confidence interval, 2.1-161.8; P = 0.009). Frailty may identify patients who would benefit from delirium-prevention strategies because of increased baseline risk for delirium.

Original languageEnglish (US)
Pages (from-to)430-435
Number of pages6
JournalAnesthesia and analgesia
Volume123
Issue number2
DOIs
StatePublished - Aug 1 2016

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

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