The Astrocyte Type I Interferon Response Is Essential for Protection against Herpes Simplex Encephalitis

Cooper K. Hayes; Daniel Giraldo; Douglas R. Wilcox; Richard Longnecker

doi:10.1128/jvi.01783-21

The Astrocyte Type I Interferon Response Is Essential for Protection against Herpes Simplex Encephalitis

Cooper K. Hayes, Daniel Giraldo, Douglas R. Wilcox, Richard Longnecker^*

^*Corresponding author for this work

Microbiology-Immunology

Research output: Contribution to journal › Letter › peer-review

2 Scopus citations

Original language	English (US)
Article number	e01783-21
Journal	Journal of virology
Volume	96
Issue number	4
DOIs	https://doi.org/10.1128/jvi.01783-21
State	Published - Feb 2022

Funding

(R01NS110631). This work, including the efforts of C.K.H., was funded by HHS, NIH, National Institute of Allergy and Infectious Diseases (NIAID) (F30AI150049), and by HHS, NIH (T32GM008152). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. We thank Nan Susmarski for her expertise in cell culture. This work, including the efforts of R.L., was funded by HHS, National Institutes of Health (NIH), National Institute of Neurological Disorders and Stroke (NINDS) (R01NS110631). This work, including the efforts of C.K.H., was funded by HHS, NIH, National Institute of Allergy and Infectious Diseases (NIAID) (F30AI150049), and by HHS, NIH (T32GM008152). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. We thank Nan Susmarski for her expertise in cell culture. This work, including the efforts of R.L., was funded by HHS, National Institutes of Health (NIH), National Institute of Neurological Disorders and Stroke (NINDS)

Keywords

Astrocytes
Encephalitis
Herpes simplex virus
Interferon
Microglia

ASJC Scopus subject areas

Insect Science
Virology
Microbiology
Immunology

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10.1128/jvi.01783-21

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@article{739e8653ce9f41b9a6b12640d6dc523b,

title = "The Astrocyte Type I Interferon Response Is Essential for Protection against Herpes Simplex Encephalitis",

keywords = "Astrocytes, Encephalitis, Herpes simplex virus, Interferon, Microglia",

author = "Hayes, {Cooper K.} and Daniel Giraldo and Wilcox, {Douglas R.} and Richard Longnecker",

note = "Funding Information: (R01NS110631). This work, including the efforts of C.K.H., was funded by HHS, NIH, National Institute of Allergy and Infectious Diseases (NIAID) (F30AI150049), and by HHS, NIH (T32GM008152). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. Funding Information: We thank Nan Susmarski for her expertise in cell culture. This work, including the efforts of R.L., was funded by HHS, National Institutes of Health (NIH), National Institute of Neurological Disorders and Stroke (NINDS) (R01NS110631). This work, including the efforts of C.K.H., was funded by HHS, NIH, National Institute of Allergy and Infectious Diseases (NIAID) (F30AI150049), and by HHS, NIH (T32GM008152). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. Funding Information: We thank Nan Susmarski for her expertise in cell culture. This work, including the efforts of R.L., was funded by HHS, National Institutes of Health (NIH), National Institute of Neurological Disorders and Stroke (NINDS)",

year = "2022",

month = feb,

doi = "10.1128/jvi.01783-21",

language = "English (US)",

volume = "96",

journal = "Journal of virology",

issn = "0022-538X",

publisher = "American Society for Microbiology",

number = "4",

}

TY - JOUR

T1 - The Astrocyte Type I Interferon Response Is Essential for Protection against Herpes Simplex Encephalitis

AU - Hayes, Cooper K.

AU - Giraldo, Daniel

AU - Wilcox, Douglas R.

AU - Longnecker, Richard

N1 - Funding Information: (R01NS110631). This work, including the efforts of C.K.H., was funded by HHS, NIH, National Institute of Allergy and Infectious Diseases (NIAID) (F30AI150049), and by HHS, NIH (T32GM008152). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. Funding Information: We thank Nan Susmarski for her expertise in cell culture. This work, including the efforts of R.L., was funded by HHS, National Institutes of Health (NIH), National Institute of Neurological Disorders and Stroke (NINDS) (R01NS110631). This work, including the efforts of C.K.H., was funded by HHS, NIH, National Institute of Allergy and Infectious Diseases (NIAID) (F30AI150049), and by HHS, NIH (T32GM008152). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. Funding Information: We thank Nan Susmarski for her expertise in cell culture. This work, including the efforts of R.L., was funded by HHS, National Institutes of Health (NIH), National Institute of Neurological Disorders and Stroke (NINDS)

PY - 2022/2

Y1 - 2022/2

KW - Astrocytes

KW - Encephalitis

KW - Herpes simplex virus

KW - Interferon

KW - Microglia

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U2 - 10.1128/jvi.01783-21

DO - 10.1128/jvi.01783-21

M3 - Letter

C2 - 34878914

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JO - Journal of virology

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The Astrocyte Type I Interferon Response Is Essential for Protection against Herpes Simplex Encephalitis

Funding

Keywords

ASJC Scopus subject areas

Access to Document

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