The atrophogenic effect of crude coal tar on human epidermis

ROBERT M. LAVKER; GARY L. GROVE; ALBERT M. KLIGMAN

doi:10.1111/j.1365-2133.1981.tb00885.x

The atrophogenic effect of crude coal tar on human epidermis

ROBERT M. LAVKER^*, GARY L. GROVE, ALBERT M. KLIGMAN

^*Corresponding author for this work

Dermatology

Research output: Contribution to journal › Article › peer-review

31 Scopus citations

Abstract

The effects of crude coal tar on human epidermis were studied in fourteen healthy young adult males. A 20%, reduction in viable epidermal thickness, as determined by computer assisted analytical microscopy, was observed after 40 days of topical treatment. Prior to this long term effect of crude coal tar, an initial transient hyperplasia was observed during the first 2 weeks of treatment. These findings indicate that crude coal tar by itself can act as a cytostatic agent on normal human skin, when applied intensively.

Original language	English (US)
Pages (from-to)	77-82
Number of pages	6
Journal	British Journal of Dermatology
Volume	105
Issue number	1
DOIs	https://doi.org/10.1111/j.1365-2133.1981.tb00885.x
State	Published - Jul 1981

ASJC Scopus subject areas

Dermatology

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1111/j.1365-2133.1981.tb00885.x

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AB - The effects of crude coal tar on human epidermis were studied in fourteen healthy young adult males. A 20%, reduction in viable epidermal thickness, as determined by computer assisted analytical microscopy, was observed after 40 days of topical treatment. Prior to this long term effect of crude coal tar, an initial transient hyperplasia was observed during the first 2 weeks of treatment. These findings indicate that crude coal tar by itself can act as a cytostatic agent on normal human skin, when applied intensively.

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The atrophogenic effect of crude coal tar on human epidermis

Abstract

ASJC Scopus subject areas

UN SDGs

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