The Carpentier-Edwards pericardial aortic valve: Ten-year results

Delos M. Cosgrove*, Bruce W. Lytle, Paul C. Taylor, Margarita T. Camacho, Robert W. Stewart, Patrick M. McCarthy, Dave P. Miller, Marion R. Piedmonte, Floyd D. Loop

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

88 Scopus citations


To evaluate the function of the Carpentier-Edwards pericardial valve in the aortic position, we analyzed the results of 310 aortic valve replacements performed between 1982 and 1985. Mean age was 64.2 ± 10.8 years (range 22 to 95 years); 190 patients (61.3%) were male patients. There were 18 hospital deaths (5.8%), and none were valve related. Follow-up of the 292 survivors was 100% complete at a mean of 7.8 ± 2.9 years; 2290 patient-years of follow-up were available for analysis. There were 133 late deaths (45.5%). Actuarial survivals at 5 and 10 years were 82.5% and 45.9%, respectively. The 10-year actuarial freedom from events was 88.7% ± 2.1% for thromboembolism, 90.9% ± 1.8% for hemorrhage, 94.3% ± 1.6% for endocarditis, and 91.2% ± 2.6% for structural deterioration. The 153 hospital survivors 65 years of age or older had an extremely low incidence of structural valve deterioration, with only four explants and 95.5% actuarial freedom from explantation at 10 years, and a linearized rate of 0.3 ± 0.2 per patient-year compared with 88.6% and 0.7 ± 0.2 for patients younger than 65 years of age. Twelve valves were explanted for structural deterioration. Of these, 11 (93%) had leaflet calcification causing stenosis and one had a wear-related leaflet tear. The Carpentier-Edwards pericardial valve has a low incidence of valve-related complications. The freedom from structural valve deterioration is low at 10 years, particularly in patients 65 years of age and older. (J THORAC CARDIOVASC SURG 1995;110: 651-62).

Original languageEnglish (US)
Pages (from-to)651-662
Number of pages12
JournalThe Journal of Thoracic and Cardiovascular Surgery
Issue number3
StatePublished - Sep 1995

ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine


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