The Chicago classification of esophageal motility disorders

Peter J. Kahrilas*, Sabine Roman, John E. Pandolfino

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations


Esophageal high-resolution manometry with esophageal pressure topography (EPT) is now the gold standard to assess esophageal motility disorders. The Chicago Classification categorizes esophageal motility in EPT based on the analysis of ten test swallows conducted in a supine posture. An algorithm is then applied which classifies motility hierarchically as achalasia, motility disorders never observed in controls (absent peristalsis, distal esophageal spasm, jackhammer esophagus) and peristaltic abnormalities statistically different than normal (frequent failed, weak, rapid, and hypertensive peristalsis). Whereas the first categories are invariably associated with esophageal symptoms, the clinical relevance of the latter category remains to be fully defined. Going forward, future investigations will focus on the classification of esophageal motility disorders after esophagogastric surgery, on the evaluation of esophagogastric junction in a context of gastroesophageal reflux disease and on UES function.

Original languageEnglish (US)
Title of host publicationSurgical Management of Benign Esophageal Disorders
Subtitle of host publicationThe "Chicago Approach"
PublisherSpringer-Verlag London Ltd
Number of pages14
ISBN (Electronic)9781447154846
ISBN (Print)1447154835, 9781447154839
StatePublished - Nov 1 2014


  • Achalasia
  • Dysphagia
  • Esophageal high-resolution manometry
  • Esophagogastric junction
  • Peristalsis
  • Spasm

ASJC Scopus subject areas

  • Medicine(all)

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