The circadian rhythm of lh release can be shifted by injections of a benzodiazepine in female golden hamsters

Fred W. Turek, Susan Losee-Olson

Research output: Contribution to journalArticlepeer-review

17 Scopus citations

Abstract

Three daily injections of the short-acting benzodiazepine, triazolam, induced pronounced phase shifts in the onset of both the circadlan surge in pituitary LH release and the circadian rhythm of locomotor activity in ovariectomized hamsters treated with estrogen. Both the magnitude and the direction of the phase shifts in these two rhythms were similar. These results indicate that a master circadian clock underlying diverse behavioral and endocrine rhythms can be reset by treatment with triazolam.

Original languageEnglish (US)
Pages (from-to)756-758
Number of pages3
JournalEndocrinology
Volume122
Issue number2
DOIs
StatePublished - Jul 23 1988

ASJC Scopus subject areas

  • Endocrinology

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