The clinical course of epidemic hemorrhagic fever

John A. Sheedy, Herman F. Froeb, Hugh A. Batson, Charles C. Conley, Joseph P. Murphy, Richard B. Hunter, David W. Cugell, Robert B. Giles, Sol C. Bershadsky, John W. Vester, Robert H. Yoe

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67 Scopus citations


1. 1. The clinical characteristics and course of epidemic hemorrhagic fever are described on the basis of observations made on United Nations forces hospitalized at the Hemorrhagic Fever Center in Korea in 1952. 2. 2. The clinical picture is characterized by sudden onset, in a person recently situated in an endemic area, of chills, fever, prostration, frontal headache, marked thirst and myalgias. There is a marked facial flush, injection of the palate and conjunctivae, and petechiae of the conjunctivae, palate, axillary folds and waist line. Proteinuria and reduction in specific gravity of the urine are present. 3. 3. The clinical course may be divided into four phases, each designated for a characteristic physiologic aberration: (1) febrile, (2) hypotensive, (3) oliguric and (4) diuretic. The presenting clinical features of each phase are described. 4. 4. Two representative case histories, one illustrating a mild course and the other a severe attack, are summarized. 5. 5. The differential diagnosis is briefly considered .

Original languageEnglish (US)
Pages (from-to)619-628
Number of pages10
JournalThe American journal of medicine
Issue number5
StatePublished - May 1954

ASJC Scopus subject areas

  • General Medicine


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