The clinical course of epidemic hemorrhagic fever

John A. Sheedy; Herman F. Froeb; Hugh A. Batson; Charles C. Conley; Joseph P. Murphy; Richard B. Hunter; David W. Cugell; Robert B. Giles; Sol C. Bershadsky; John W. Vester; Robert H. Yoe

doi:10.1016/0002-9343(54)90268-5

The clinical course of epidemic hemorrhagic fever

John A. Sheedy, Herman F. Froeb, Hugh A. Batson, Charles C. Conley, Joseph P. Murphy, Richard B. Hunter, David W. Cugell, Robert B. Giles, Sol C. Bershadsky, John W. Vester, Robert H. Yoe

Medicine

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Abstract

1. 1. The clinical characteristics and course of epidemic hemorrhagic fever are described on the basis of observations made on United Nations forces hospitalized at the Hemorrhagic Fever Center in Korea in 1952. 2. 2. The clinical picture is characterized by sudden onset, in a person recently situated in an endemic area, of chills, fever, prostration, frontal headache, marked thirst and myalgias. There is a marked facial flush, injection of the palate and conjunctivae, and petechiae of the conjunctivae, palate, axillary folds and waist line. Proteinuria and reduction in specific gravity of the urine are present. 3. 3. The clinical course may be divided into four phases, each designated for a characteristic physiologic aberration: (1) febrile, (2) hypotensive, (3) oliguric and (4) diuretic. The presenting clinical features of each phase are described. 4. 4. Two representative case histories, one illustrating a mild course and the other a severe attack, are summarized. 5. 5. The differential diagnosis is briefly considered .

Original language	English (US)
Pages (from-to)	619-628
Number of pages	10
Journal	The American journal of medicine
Volume	16
Issue number	5
DOIs	https://doi.org/10.1016/0002-9343(54)90268-5
State	Published - May 1954

Funding

Acknowledgment: Sponsored by the Commission on Hemorrhagic Fever of the Armed Forces Epidemiological Board, and supported by the Office of the Surgeon General, Department of the Army.

ASJC Scopus subject areas

General Medicine

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10.1016/0002-9343(54)90268-5

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title = "The clinical course of epidemic hemorrhagic fever",

abstract = "1. 1. The clinical characteristics and course of epidemic hemorrhagic fever are described on the basis of observations made on United Nations forces hospitalized at the Hemorrhagic Fever Center in Korea in 1952. 2. 2. The clinical picture is characterized by sudden onset, in a person recently situated in an endemic area, of chills, fever, prostration, frontal headache, marked thirst and myalgias. There is a marked facial flush, injection of the palate and conjunctivae, and petechiae of the conjunctivae, palate, axillary folds and waist line. Proteinuria and reduction in specific gravity of the urine are present. 3. 3. The clinical course may be divided into four phases, each designated for a characteristic physiologic aberration: (1) febrile, (2) hypotensive, (3) oliguric and (4) diuretic. The presenting clinical features of each phase are described. 4. 4. Two representative case histories, one illustrating a mild course and the other a severe attack, are summarized. 5. 5. The differential diagnosis is briefly considered .",

author = "Sheedy, {John A.} and Froeb, {Herman F.} and Batson, {Hugh A.} and Conley, {Charles C.} and Murphy, {Joseph P.} and Hunter, {Richard B.} and Cugell, {David W.} and Giles, {Robert B.} and Bershadsky, {Sol C.} and Vester, {John W.} and Yoe, {Robert H.}",

note = "Funding Information: Acknowledgment: Sponsored by the Commission on Hemorrhagic Fever of the Armed Forces Epidemiological Board, and supported by the Office of the Surgeon General, Department of the Army.",

year = "1954",

month = may,

doi = "10.1016/0002-9343(54)90268-5",

language = "English (US)",

volume = "16",

pages = "619--628",

journal = "The American journal of medicine",

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AU - Sheedy, John A.

AU - Froeb, Herman F.

AU - Batson, Hugh A.

AU - Conley, Charles C.

AU - Murphy, Joseph P.

AU - Hunter, Richard B.

AU - Cugell, David W.

AU - Giles, Robert B.

AU - Bershadsky, Sol C.

AU - Vester, John W.

AU - Yoe, Robert H.

N1 - Funding Information: Acknowledgment: Sponsored by the Commission on Hemorrhagic Fever of the Armed Forces Epidemiological Board, and supported by the Office of the Surgeon General, Department of the Army.

PY - 1954/5

Y1 - 1954/5

N2 - 1. 1. The clinical characteristics and course of epidemic hemorrhagic fever are described on the basis of observations made on United Nations forces hospitalized at the Hemorrhagic Fever Center in Korea in 1952. 2. 2. The clinical picture is characterized by sudden onset, in a person recently situated in an endemic area, of chills, fever, prostration, frontal headache, marked thirst and myalgias. There is a marked facial flush, injection of the palate and conjunctivae, and petechiae of the conjunctivae, palate, axillary folds and waist line. Proteinuria and reduction in specific gravity of the urine are present. 3. 3. The clinical course may be divided into four phases, each designated for a characteristic physiologic aberration: (1) febrile, (2) hypotensive, (3) oliguric and (4) diuretic. The presenting clinical features of each phase are described. 4. 4. Two representative case histories, one illustrating a mild course and the other a severe attack, are summarized. 5. 5. The differential diagnosis is briefly considered .

AB - 1. 1. The clinical characteristics and course of epidemic hemorrhagic fever are described on the basis of observations made on United Nations forces hospitalized at the Hemorrhagic Fever Center in Korea in 1952. 2. 2. The clinical picture is characterized by sudden onset, in a person recently situated in an endemic area, of chills, fever, prostration, frontal headache, marked thirst and myalgias. There is a marked facial flush, injection of the palate and conjunctivae, and petechiae of the conjunctivae, palate, axillary folds and waist line. Proteinuria and reduction in specific gravity of the urine are present. 3. 3. The clinical course may be divided into four phases, each designated for a characteristic physiologic aberration: (1) febrile, (2) hypotensive, (3) oliguric and (4) diuretic. The presenting clinical features of each phase are described. 4. 4. Two representative case histories, one illustrating a mild course and the other a severe attack, are summarized. 5. 5. The differential diagnosis is briefly considered .

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The clinical course of epidemic hemorrhagic fever

Abstract

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