The clinical-electrographic expression of infantile seizures

Christian M. Korff, Douglas R. Nordli

Research output: Contribution to journalArticlepeer-review

14 Scopus citations


Purpose: To describe the electro-clinical expression of seizures in infants (1-24 months). Methods: We reviewed the video and EEG files of allinfantile seizures recorded at Children's Memorial Hospital, Chicago,IL, from 2000 to 2005. Electrographic and clinical features were entered into separate databases. The electrographic component of the database analyzed the predominant location and pattern at onset, the evolution, the termination and the duration of each seizure. The clinicaldata sheet included 25 items. Each seizurewas assigned to a specific category according to its most prominent clinical feature, according to the opinion of both observers. Results: Thirteen seizure types were identified. In a significant number of cases, the EEG correlate could not be predicted on the basis of clinical observations only. Generalized seizures were observed, on average, at a later age than focal seizures. Excluding spasms, the mean duration of seizures was short (36 s). Conclusions: The results of this study are useful in describing the clinical and electrographic repertoire of infantile seizures. The findings show that video-EEG recordings in infants with frequent, recurrent seizures are useful by fully allowing complete recognition of subtle events, and in fully categorizing the true nature of theictus. Video-EEG findings and accurate seizure classification may add fundamental information with regards to epilepsy syndrome diagnosis andspecific treatment options, including surgery.

Original languageEnglish (US)
Pages (from-to)S116-S131
JournalEpilepsy Research
Issue numberSUPPL.1
StatePublished - Aug 1 2006


  • Electro-clinical expression.
  • Infants
  • Seizures

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology


Dive into the research topics of 'The clinical-electrographic expression of infantile seizures'. Together they form a unique fingerprint.

Cite this