TY - JOUR
T1 - The Clinical Impact of Implementation of a Multidisciplinary Endocarditis Team
AU - El-Dalati, Sami
AU - Cronin, Daniel
AU - Riddell, James
AU - Shea, Michael
AU - Weinberg, Richard L.
AU - Washer, Laraine
AU - Stoneman, Emily
AU - Perry, D. Alexander
AU - Bradley, Suzanne
AU - Burke, James
AU - Murali, Sadhana
AU - Fagan, Christopher
AU - Chanderraj, Rishi
AU - Christine, Paul
AU - Patel, Twisha
AU - Ressler, Kirra
AU - Fukuhara, Shinichi
AU - Romano, Matthew
AU - Yang, Bo
AU - Deeb, George Michael
N1 - Funding Information:
The authors wish to acknowledge Elizabeth O'Donnell, PhD, who reviewed an earlier draft of the manuscript.
Publisher Copyright:
© 2022 The Society of Thoracic Surgeons
PY - 2022/1
Y1 - 2022/1
N2 - Background: Infectious endocarditis is associated with substantial in-hospital mortality of 15%-20%. Effective management requires coordination between multiple medical and surgical subspecialties, which can often lead to disjointed care. Previous European studies have identified multidisciplinary endocarditis teams as a tool for reducing endocarditis mortality. Methods: The multidisciplinary endocarditis team was formed in May 2018. The group developed an evidence-based algorithm for management of endocarditis that was used to provide recommendations for hospitalized patients over a 1-year period. Mortality outcomes were then retroactively assessed and compared to a historical control utilizing propensity matching. Results: Between June 2018 and June 2019 the team provided guideline-based recommendations on 56 patients with Duke Criteria–definite endocarditis and at least 1 American Heart Association indication for surgery. The historical control included 68 patients with definite endocarditis and surgical indications admitted between July 1, 2014, and June 30, 2015. In-hospital mortality decreased significantly from 29.4% in 2014-2015 to 7.1% in 2018-2019 (P < .0001). There was a non-significant increase in the rate of surgical intervention after implementation of the team (41.2% vs 55.4%; P = 0.12). Propensity score matching demonstrated similar results. Conclusions: Implementation of a multidisciplinary endocarditis team was associated with a significant 1-year decrease in all-cause in-hospital mortality for patients with definite endocarditis and surgical indications, in the presence of notable differences between the 2 studied cohorts. In conjunction with previous studies demonstrating their effectiveness, these data support the idea that widespread adoption of endocarditis teams in North America could improve outcomes for this patient population.
AB - Background: Infectious endocarditis is associated with substantial in-hospital mortality of 15%-20%. Effective management requires coordination between multiple medical and surgical subspecialties, which can often lead to disjointed care. Previous European studies have identified multidisciplinary endocarditis teams as a tool for reducing endocarditis mortality. Methods: The multidisciplinary endocarditis team was formed in May 2018. The group developed an evidence-based algorithm for management of endocarditis that was used to provide recommendations for hospitalized patients over a 1-year period. Mortality outcomes were then retroactively assessed and compared to a historical control utilizing propensity matching. Results: Between June 2018 and June 2019 the team provided guideline-based recommendations on 56 patients with Duke Criteria–definite endocarditis and at least 1 American Heart Association indication for surgery. The historical control included 68 patients with definite endocarditis and surgical indications admitted between July 1, 2014, and June 30, 2015. In-hospital mortality decreased significantly from 29.4% in 2014-2015 to 7.1% in 2018-2019 (P < .0001). There was a non-significant increase in the rate of surgical intervention after implementation of the team (41.2% vs 55.4%; P = 0.12). Propensity score matching demonstrated similar results. Conclusions: Implementation of a multidisciplinary endocarditis team was associated with a significant 1-year decrease in all-cause in-hospital mortality for patients with definite endocarditis and surgical indications, in the presence of notable differences between the 2 studied cohorts. In conjunction with previous studies demonstrating their effectiveness, these data support the idea that widespread adoption of endocarditis teams in North America could improve outcomes for this patient population.
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U2 - 10.1016/j.athoracsur.2021.02.027
DO - 10.1016/j.athoracsur.2021.02.027
M3 - Article
C2 - 33662308
AN - SCOPUS:85114678309
SN - 0003-4975
VL - 113
SP - 118
EP - 124
JO - Annals of Thoracic Surgery
JF - Annals of Thoracic Surgery
IS - 1
ER -