The construction of movement by the spinal cord

Matthew C. Tresch; Philippe Saltiel; Emilio Bizzi

doi:10.1038/5721

The construction of movement by the spinal cord

Matthew C. Tresch, Philippe Saltiel, Emilio Bizzi^*

^*Corresponding author for this work

Biomedical Engineering

Research output: Contribution to journal › Article › peer-review

503 Scopus citations

Abstract

We used a computational analysis to identify the basic elements with which the vertebrate spinal cord constructs one complex behavior. This analysis extracted a small set of muscle synergies from the range of muscle activations generated by cutaneous stimulation of the frog hindlimb. The flexible combination of these synergies was able to account for the large number of different motor patterns produced by different animals. These results therefore demonstrate one strategy used by the vertebrate nervous system to produce movement in a computationally simple manner.

Original language	English (US)
Pages (from-to)	162-167
Number of pages	6
Journal	Nature neuroscience
Volume	2
Issue number	2
DOIs	https://doi.org/10.1038/5721
State	Published - Feb 1999

Funding

We thank Sandro Mussa-Ivaldi and Andrea d’Avella for reading versions of this manuscript and Simon Giszter, Peter Dayan, Kuno Wyler and James Galagan for suggestions. M.C.T. was supported by a HHMI predoctoral fellowship. This research was supported by NIH NS09343 and ONR N00014-95-I0445 to E.B.

ASJC Scopus subject areas

General Neuroscience

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10.1038/5721

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The construction of movement by the spinal cord

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