The construction of movement by the spinal cord

Matthew C. Tresch; Philippe Saltiel; Emilio Bizzi

doi:10.1038/5721

The construction of movement by the spinal cord

Matthew C. Tresch, Philippe Saltiel, Emilio Bizzi^*

^*Corresponding author for this work

Biomedical Engineering

Research output: Contribution to journal › Article › peer-review

464 Scopus citations

Abstract

We used a computational analysis to identify the basic elements with which the vertebrate spinal cord constructs one complex behavior. This analysis extracted a small set of muscle synergies from the range of muscle activations generated by cutaneous stimulation of the frog hindlimb. The flexible combination of these synergies was able to account for the large number of different motor patterns produced by different animals. These results therefore demonstrate one strategy used by the vertebrate nervous system to produce movement in a computationally simple manner.

Original language	English (US)
Pages (from-to)	162-167
Number of pages	6
Journal	Nature neuroscience
Volume	2
Issue number	2
DOIs	https://doi.org/10.1038/5721
State	Published - Feb 1999

ASJC Scopus subject areas

Neuroscience(all)

Access to Document

10.1038/5721

Cite this

@article{9a0f4599de724c74b2ce650d4d25f351,

title = "The construction of movement by the spinal cord",

abstract = "We used a computational analysis to identify the basic elements with which the vertebrate spinal cord constructs one complex behavior. This analysis extracted a small set of muscle synergies from the range of muscle activations generated by cutaneous stimulation of the frog hindlimb. The flexible combination of these synergies was able to account for the large number of different motor patterns produced by different animals. These results therefore demonstrate one strategy used by the vertebrate nervous system to produce movement in a computationally simple manner.",

author = "Tresch, {Matthew C.} and Philippe Saltiel and Emilio Bizzi",

note = "Funding Information: We thank Sandro Mussa-Ivaldi and Andrea d{\textquoteright}Avella for reading versions of this manuscript and Simon Giszter, Peter Dayan, Kuno Wyler and James Galagan for suggestions. M.C.T. was supported by a HHMI predoctoral fellowship. This research was supported by NIH NS09343 and ONR N00014-95-I0445 to E.B. Copyright: Copyright 2007 Elsevier B.V., All rights reserved.",

year = "1999",

month = feb,

doi = "10.1038/5721",

language = "English (US)",

volume = "2",

pages = "162--167",

journal = "Nature Neuroscience",

issn = "1097-6256",

publisher = "Nature Publishing Group",

number = "2",

}

TY - JOUR

T1 - The construction of movement by the spinal cord

AU - Tresch, Matthew C.

AU - Saltiel, Philippe

AU - Bizzi, Emilio

N1 - Funding Information: We thank Sandro Mussa-Ivaldi and Andrea d’Avella for reading versions of this manuscript and Simon Giszter, Peter Dayan, Kuno Wyler and James Galagan for suggestions. M.C.T. was supported by a HHMI predoctoral fellowship. This research was supported by NIH NS09343 and ONR N00014-95-I0445 to E.B. Copyright: Copyright 2007 Elsevier B.V., All rights reserved.

PY - 1999/2

Y1 - 1999/2

N2 - We used a computational analysis to identify the basic elements with which the vertebrate spinal cord constructs one complex behavior. This analysis extracted a small set of muscle synergies from the range of muscle activations generated by cutaneous stimulation of the frog hindlimb. The flexible combination of these synergies was able to account for the large number of different motor patterns produced by different animals. These results therefore demonstrate one strategy used by the vertebrate nervous system to produce movement in a computationally simple manner.

AB - We used a computational analysis to identify the basic elements with which the vertebrate spinal cord constructs one complex behavior. This analysis extracted a small set of muscle synergies from the range of muscle activations generated by cutaneous stimulation of the frog hindlimb. The flexible combination of these synergies was able to account for the large number of different motor patterns produced by different animals. These results therefore demonstrate one strategy used by the vertebrate nervous system to produce movement in a computationally simple manner.

UR - http://www.scopus.com/inward/record.url?scp=0033365630&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0033365630&partnerID=8YFLogxK

U2 - 10.1038/5721

DO - 10.1038/5721

M3 - Article

C2 - 10195201

AN - SCOPUS:0033365630

SN - 1097-6256

VL - 2

SP - 162

EP - 167

JO - Nature Neuroscience

JF - Nature Neuroscience

IS - 2

ER -

The construction of movement by the spinal cord

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this