Abstract
Bivalently marked chromatin, containing both histone H3 lysine 4 (H3K4) and H3K27 trimethylation, is a hallmark of developmentally regulated paused promoters in mammalian embryonic stem cells. In this issue of Developmental Cell, Akkers et al. report that Xenopus tropicalis embryos transition through early development without the requirement for bivalently marked promoters.
Original language | English (US) |
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Pages (from-to) | 301-303 |
Number of pages | 3 |
Journal | Developmental Cell |
Volume | 17 |
Issue number | 3 |
DOIs | |
State | Published - Sep 15 2009 |
ASJC Scopus subject areas
- Molecular Biology
- General Biochemistry, Genetics and Molecular Biology
- Developmental Biology
- Cell Biology