The early use of minimal enteral nutrition in extremely low birth weight newborns

E. Mosqueda*, L. Sapiegiene, L. Glynn, D. Wilson-Costello, M. Weiss

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

18 Scopus citations

Abstract

Objective: To gather information regarding the efficacy of early minimal enteral nutrition on overall feeding tolerance in extremely low birth weight infants. Study Design: Prospective randomized controlled trial comparing the early use of minimal enteral nutrition in extremely low birth weight infants from day 2 to day 7 vs control infants. On day 8, feeding volume in both groups were advanced by 10ml kg-1day-1 until full enteral feedings were reached. Time to full feeds, number of intolerance episodes, anthropometric measurements, peak total bilirubin levels, incidence of necrotizing enterocolitis and incidence of sepsis were compared between the two groups with t-test and χ2 test. Result: Eighty-four infants were enrolled in the study but only 61 infants completed the feeding protocol. No statistically significant differences were found between the groups with regards to growth patterns, feeding tolerance, mortality, length of hospital stay and incidence of sepsis and necrotizing enterocolitis. Conclusion: Early minimal enteral nutrition use in extremely low birth weight infants did not improve feeding tolerance.

Original languageEnglish (US)
Pages (from-to)264-269
Number of pages6
JournalJournal of Perinatology
Volume28
Issue number4
DOIs
StatePublished - Apr 2008

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynecology

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