The effect of ancrod on the delayed hypersensitivity response in rats

S. Silberman, H. C. Kwaan

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Delayed hypersensitivity was induced in rats by means of sheep erythrocytes and bovine serum albumin lipid conjugate. Administration of heparin to rats sensitized to either antigen resulted in diminution of the delayed hypersensitivity reaction. Administration of ancrod, however, failed to inhibit the delayed cellular reaction to either antigen. Granuloma formation remained unaffected when rats were injected with either heparin or ancrod. The lack of ancrod effect, in contrast to heparin effect, on delayed hypersensitivity is discussed.

Original languageEnglish (US)
Pages (from-to)44-51
Number of pages8
JournalBritish Journal of Experimental Pathology
Volume56
Issue number1
StatePublished - Jan 1 1975

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

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