The effect of blastomere biopsy on preimplantation mouse embryo development and global gene expression

Francesca E. Duncan, Paula Stein, Carmen J. Williams, Richard M. Schultz*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

23 Scopus citations

Abstract

The blastomere biopsy procedure does not affect preimplantation embryo development or global patterns of gene expression in a mouse model of Preimplantation Genetic Testing (PGT). However, zona breaching, which is inherent to the blastomere biopsy procedure, causes significant premature and sometimes abnormal hatching.

Original languageEnglish (US)
Pages (from-to)1462-1465
Number of pages4
JournalFertility and Sterility
Volume91
Issue number4 SUPPL.
DOIs
StatePublished - Apr 2009

ASJC Scopus subject areas

  • Reproductive Medicine
  • Obstetrics and Gynecology

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