Here we describe differences in the formation of the epinephrine-induced Ca2+ transients between parent and Ki-ras- transformed NIH3T3 fibroblasts. These transients proved to be the results of an efflux from both the thapsigargin-sensitive and-insensitive intracellular pools. While the epinephrine-induced detachment of the ras-transformed cells might be due to cytoskeletal and/or cell-matrix alterations.
|Original language||English (US)|
|Number of pages||9|
|Journal||Biochemical and Biophysical Research Communications|
|State||Published - 1993|
ASJC Scopus subject areas
- Molecular Biology
- Cell Biology