The effect of ligands on FePt-Fe3O4 core-shell magnetic nanoparticles

Dong Hyun Kim; Yoshinori Tamada; Teruo Ono; Samuel D. Bader; Elena A. Rozhkova; Valentyn Novosad

doi:10.1166/jnn.2014.8471

The effect of ligands on FePt-Fe₃O₄ core-shell magnetic nanoparticles

Dong Hyun Kim, Yoshinori Tamada, Teruo Ono, Samuel D. Bader, Elena A. Rozhkova^*, Valentyn Novosad

^*Corresponding author for this work

Radiology

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

FePt-Fe₃O₄ core-shell nanoparticles functionalized with 3,4-dihydroxyphenylacetic acid (DOPAC) and dimercaptosuccinic acid (DMSA) ligands were synthesized and characterized. We found that the DOPAC ligand enhances the magnetic properties of the FePt-Fe₃O₄ particles, in comparison with the DMSA ligand, which induces the oxidation of the shell layer that causes a significant reduction of the saturation magnetization. The synthesized magnetic nanoparticles were evaluated for applications in magnetic hyperthermia and magnetic resonance imaging contrast enhancement.

Original language	English (US)
Pages (from-to)	2648-2652
Number of pages	5
Journal	Journal of Nanoscience and Nanotechnology
Volume	14
Issue number	3
DOIs	https://doi.org/10.1166/jnn.2014.8471
State	Published - Mar 2014

Keywords

3,4-dihydroxyphenylacetic acid (DOPAC)
Dimercaptosuccinic acid (DMSA)
FeO
FePt
Magnetic nanoparticles
Surface functionalization

ASJC Scopus subject areas

General Chemistry
Condensed Matter Physics
Bioengineering
Biomedical Engineering
General Materials Science

Access to Document

10.1166/jnn.2014.8471

Cite this

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title = "The effect of ligands on FePt-Fe3O4 core-shell magnetic nanoparticles",

abstract = "FePt-Fe3O4 core-shell nanoparticles functionalized with 3,4-dihydroxyphenylacetic acid (DOPAC) and dimercaptosuccinic acid (DMSA) ligands were synthesized and characterized. We found that the DOPAC ligand enhances the magnetic properties of the FePt-Fe3O4 particles, in comparison with the DMSA ligand, which induces the oxidation of the shell layer that causes a significant reduction of the saturation magnetization. The synthesized magnetic nanoparticles were evaluated for applications in magnetic hyperthermia and magnetic resonance imaging contrast enhancement.",

keywords = "3,4-dihydroxyphenylacetic acid (DOPAC), Dimercaptosuccinic acid (DMSA), FeO, FePt, Magnetic nanoparticles, Surface functionalization",

author = "Kim, {Dong Hyun} and Yoshinori Tamada and Teruo Ono and Bader, {Samuel D.} and Rozhkova, {Elena A.} and Valentyn Novosad",

year = "2014",

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T1 - The effect of ligands on FePt-Fe3O4 core-shell magnetic nanoparticles

AU - Kim, Dong Hyun

AU - Tamada, Yoshinori

AU - Ono, Teruo

AU - Bader, Samuel D.

AU - Rozhkova, Elena A.

AU - Novosad, Valentyn

PY - 2014/3

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N2 - FePt-Fe3O4 core-shell nanoparticles functionalized with 3,4-dihydroxyphenylacetic acid (DOPAC) and dimercaptosuccinic acid (DMSA) ligands were synthesized and characterized. We found that the DOPAC ligand enhances the magnetic properties of the FePt-Fe3O4 particles, in comparison with the DMSA ligand, which induces the oxidation of the shell layer that causes a significant reduction of the saturation magnetization. The synthesized magnetic nanoparticles were evaluated for applications in magnetic hyperthermia and magnetic resonance imaging contrast enhancement.

AB - FePt-Fe3O4 core-shell nanoparticles functionalized with 3,4-dihydroxyphenylacetic acid (DOPAC) and dimercaptosuccinic acid (DMSA) ligands were synthesized and characterized. We found that the DOPAC ligand enhances the magnetic properties of the FePt-Fe3O4 particles, in comparison with the DMSA ligand, which induces the oxidation of the shell layer that causes a significant reduction of the saturation magnetization. The synthesized magnetic nanoparticles were evaluated for applications in magnetic hyperthermia and magnetic resonance imaging contrast enhancement.

KW - 3,4-dihydroxyphenylacetic acid (DOPAC)

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KW - FePt

KW - Magnetic nanoparticles

KW - Surface functionalization

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