TY - JOUR
T1 - The Effects of Repetition on Memory Performance in Cognitively Impaired Patients
AU - Weingartner, Herbert
AU - Eckardt, Michael
AU - Grafman, Jordan
AU - Molchan, Susan
AU - Putnam, Karen
AU - Rawlings, Robert
AU - Sunderland, Trey
PY - 1993/1/1
Y1 - 1993/1/1
N2 - Patients diagnosed with Alzheimer's disease (AD; n = 37), alcohol amnestic disorder (AMD; n = 9), major depression (n = 16), as well as elderly normal volunteers (n = 48), are differentially sensitive to the effects of repetition on memory. Three learning and memory procedures were used to demonstrate that repeated words were more likely to be recalled by elderly normal volunteers than by AD patients. This insensitivity to repetition effects in AD is attributed to an impairment in generating information from semantic memory, which forms the basis of the cognitive context that is used to rehearse and encode to-be-remembered words. In contrast, depressed patients were particularly sensitive to the effects of repetition on recall. AMD patients also recalled more words that were repeated than words that were presented only once, but this effect was attenuated compared with the response expressed in normal volunteers.
AB - Patients diagnosed with Alzheimer's disease (AD; n = 37), alcohol amnestic disorder (AMD; n = 9), major depression (n = 16), as well as elderly normal volunteers (n = 48), are differentially sensitive to the effects of repetition on memory. Three learning and memory procedures were used to demonstrate that repeated words were more likely to be recalled by elderly normal volunteers than by AD patients. This insensitivity to repetition effects in AD is attributed to an impairment in generating information from semantic memory, which forms the basis of the cognitive context that is used to rehearse and encode to-be-remembered words. In contrast, depressed patients were particularly sensitive to the effects of repetition on recall. AMD patients also recalled more words that were repeated than words that were presented only once, but this effect was attenuated compared with the response expressed in normal volunteers.
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U2 - 10.1037/0894-4105.7.3.385
DO - 10.1037/0894-4105.7.3.385
M3 - Article
AN - SCOPUS:0000714015
VL - 7
SP - 385
EP - 395
JO - Neuropsychology
JF - Neuropsychology
SN - 0894-4105
IS - 3
ER -