TY - JOUR
T1 - The effects of subinhibitory concentrations of various antibiotics on phagocytosis of Streptococcus faecalis
AU - Kennedy, E. M.
AU - Snowden, N.
AU - Westenfelder, G.
AU - Phair, J. P.
PY - 1983
Y1 - 1983
N2 - This study reports the effects of subinhibitory concentrations of the antibiotics, clindamycin, gentamicin, moxalactam, and penicillin G, against 6 blood isolates of Streptococcus faecalis to determine possible enhancement of phagocytosis. In addition, combinations of penicillin G plus streptomycin, penicillin G and gentamicin, and clindamycin plus gentamicin were studied to determine synergistic growth inhibition. Results suggest no observable effect in phagocytosis from subinhibitory concentrations of the studied antibiotics singly or in combination. The number of viable intracellular Str. faecalis were also not affected by pre-treatment with antibiotics.
AB - This study reports the effects of subinhibitory concentrations of the antibiotics, clindamycin, gentamicin, moxalactam, and penicillin G, against 6 blood isolates of Streptococcus faecalis to determine possible enhancement of phagocytosis. In addition, combinations of penicillin G plus streptomycin, penicillin G and gentamicin, and clindamycin plus gentamicin were studied to determine synergistic growth inhibition. Results suggest no observable effect in phagocytosis from subinhibitory concentrations of the studied antibiotics singly or in combination. The number of viable intracellular Str. faecalis were also not affected by pre-treatment with antibiotics.
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U2 - 10.1093/jac/12.suppl_c.69
DO - 10.1093/jac/12.suppl_c.69
M3 - Article
C2 - 6417102
AN - SCOPUS:0021085734
SN - 0305-7453
VL - 12
SP - 69
EP - 74
JO - Journal of antimicrobial chemotherapy
JF - Journal of antimicrobial chemotherapy
IS - SUPPL. C
ER -
