The effects of ultrasound-guided shock waves during early pregnancy in Sprague-Dawley rats

D. P. Smith; J. B. Graham; J. B. Prystowsky; B. L. Dalkin; A. A. Nemcek

doi:10.1016/S0022-5347(17)37203-8

The effects of ultrasound-guided shock waves during early pregnancy in Sprague-Dawley rats

D. P. Smith^*, J. B. Graham, J. B. Prystowsky, B. L. Dalkin, A. A. Nemcek

^*Corresponding author for this work

Radiology

Research output: Contribution to journal › Article › peer-review

37 Scopus citations

Abstract

Pregnancy is a contraindication to extracorporeal shock wave lithotripsy (ESWL) because of its possible harm to the embryo or fetus caused by shock waves or ionizing radiation. In this study timed-pregnant rats were subjected to shock waves early in gestation using a lithotriptor having ultrasound imaging. In a pilot group undergoing immediate laparotomy, it was determined to what extent the pelvic structures were effected. Then a test group was exposed to shock waves and carried to near term pregnancy along with an identical group of pregnant, sham procedure rats. At laparotomy all were inspected for fetal viability, fetal abnormalities, and maternal organ damage. Fetuses located nearest the focal area of maximum shock wave energy showed lower mean weight than controls. There was no recognizable gross or microscopic fetal damage.

Original language	English (US)
Pages (from-to)	231-234
Number of pages	4
Journal	Journal of Urology
Volume	147
Issue number	1
DOIs	https://doi.org/10.1016/S0022-5347(17)37203-8
State	Published - 1992

Keywords

fetus
lithotripsy
pregnancy
shock waves

ASJC Scopus subject areas

Urology

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10.1016/S0022-5347(17)37203-8

Cite this

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abstract = "Pregnancy is a contraindication to extracorporeal shock wave lithotripsy (ESWL) because of its possible harm to the embryo or fetus caused by shock waves or ionizing radiation. In this study timed-pregnant rats were subjected to shock waves early in gestation using a lithotriptor having ultrasound imaging. In a pilot group undergoing immediate laparotomy, it was determined to what extent the pelvic structures were effected. Then a test group was exposed to shock waves and carried to near term pregnancy along with an identical group of pregnant, sham procedure rats. At laparotomy all were inspected for fetal viability, fetal abnormalities, and maternal organ damage. Fetuses located nearest the focal area of maximum shock wave energy showed lower mean weight than controls. There was no recognizable gross or microscopic fetal damage.",

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AU - Dalkin, B. L.

AU - Nemcek, A. A.

PY - 1992

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The effects of ultrasound-guided shock waves during early pregnancy in Sprague-Dawley rats

Abstract

Keywords

ASJC Scopus subject areas

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