The efficacy and safety of synchronous bilateral extracorporeal shock wave lithotripsy

Kent T Perry Jr, Norm D. Smith, Adam C. Weiser, Herbert M. User, Shilajit D Kundu, Robert B Nadler*

*Corresponding author for this work

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Purpose: Bilateral renal calculi have traditionally been managed by staged extracorporeal shock wave lithotripsy (ESWL) due to concern about bilateral obstruction. We evaluated the safety and efficacy of synchronous bilateral ESWL in a large series of patients treated at our institution to determine the safety and efficacy of this controversial technique in what is to our knowledge the largest series to date. Materials and Methods: We retrospectively evaluated the records of 120 patients with a mean age of 48 years who underwent bilateral synchronous ESWL between 1987 and 1996. Of the patients 71 (59%) were male. Average followup was 21 months. ESWL was performed using a Dornier HM3 lithotriptor in all cases. Intraoperative technique and postoperative factors were analyzed using the Pearson product moment correlation, the 2-tailed t test and multiple regression analysis. Results: Mean stone size was 13 and 15 mm. on the left and right sides, respectively. There was an average of 1.7 stones per renal unit. After i treatment 72 of the 120 patients (60%) were stone-free bilaterally, while 72% and 73% of left and right renal units, respectively, were also stone-free. Mean creatinine was similar preoperatively and postoperatively (1.46 and 1.41 mg./dl., respectively, p = 0.73). There was i or more complications in 18 cases. The majority of complications were minor with no long-term morbidity or death and there was no case of bilateral obstruction or renal failure. Additional procedures were required in 19 patients (16%) due to significant residual stone disease or obstruction during followup. Multiple regression analysis revealed that only patient age, a right ureteral stent and the number of shocks correlated with the complication rate. Stone size and number independently increased the probability of treatment failure and a repeat procedure (p < 0.05). Patients with stones 20 mm. or greater were at particularly high risk for treatment failure and additional procedures. A total of 27 of the 35 patients (77%) with residual calculi and 13 of the 19 (68%) requiring additional procedures were in this high risk subgroup. Conclusions: Bilateral synchronous ESWL is safe and effective monotherapy for bilateral urolithiasis. No patient had bilateral obstruction or renal failure and no deterioration of renal function was detected at followup. Knowing which patient populations are at higher risk for failure or complications may guide decision making.

Original languageEnglish (US)
Pages (from-to)644-647
Number of pages4
JournalJournal of Urology
Volume164
Issue number3 I
StatePublished - Jan 1 2000

Fingerprint

Lithotripsy
Safety
Treatment Failure
Kidney
Renal Insufficiency
Regression Analysis
Urolithiasis
Kidney Calculi
Calculi
Stents
Shock
Creatinine
Decision Making
Morbidity

Keywords

  • Calculi
  • Extracorporeal shockwave lithotripsy
  • Kidney

ASJC Scopus subject areas

  • Urology

Cite this

@article{b02c71cbe4e64cff9f39f5be427e2c4c,
title = "The efficacy and safety of synchronous bilateral extracorporeal shock wave lithotripsy",
abstract = "Purpose: Bilateral renal calculi have traditionally been managed by staged extracorporeal shock wave lithotripsy (ESWL) due to concern about bilateral obstruction. We evaluated the safety and efficacy of synchronous bilateral ESWL in a large series of patients treated at our institution to determine the safety and efficacy of this controversial technique in what is to our knowledge the largest series to date. Materials and Methods: We retrospectively evaluated the records of 120 patients with a mean age of 48 years who underwent bilateral synchronous ESWL between 1987 and 1996. Of the patients 71 (59{\%}) were male. Average followup was 21 months. ESWL was performed using a Dornier HM3 lithotriptor in all cases. Intraoperative technique and postoperative factors were analyzed using the Pearson product moment correlation, the 2-tailed t test and multiple regression analysis. Results: Mean stone size was 13 and 15 mm. on the left and right sides, respectively. There was an average of 1.7 stones per renal unit. After i treatment 72 of the 120 patients (60{\%}) were stone-free bilaterally, while 72{\%} and 73{\%} of left and right renal units, respectively, were also stone-free. Mean creatinine was similar preoperatively and postoperatively (1.46 and 1.41 mg./dl., respectively, p = 0.73). There was i or more complications in 18 cases. The majority of complications were minor with no long-term morbidity or death and there was no case of bilateral obstruction or renal failure. Additional procedures were required in 19 patients (16{\%}) due to significant residual stone disease or obstruction during followup. Multiple regression analysis revealed that only patient age, a right ureteral stent and the number of shocks correlated with the complication rate. Stone size and number independently increased the probability of treatment failure and a repeat procedure (p < 0.05). Patients with stones 20 mm. or greater were at particularly high risk for treatment failure and additional procedures. A total of 27 of the 35 patients (77{\%}) with residual calculi and 13 of the 19 (68{\%}) requiring additional procedures were in this high risk subgroup. Conclusions: Bilateral synchronous ESWL is safe and effective monotherapy for bilateral urolithiasis. No patient had bilateral obstruction or renal failure and no deterioration of renal function was detected at followup. Knowing which patient populations are at higher risk for failure or complications may guide decision making.",
keywords = "Calculi, Extracorporeal shockwave lithotripsy, Kidney",
author = "{Perry Jr}, {Kent T} and Smith, {Norm D.} and Weiser, {Adam C.} and User, {Herbert M.} and Kundu, {Shilajit D} and Nadler, {Robert B}",
year = "2000",
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language = "English (US)",
volume = "164",
pages = "644--647",
journal = "Journal of Urology",
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}

The efficacy and safety of synchronous bilateral extracorporeal shock wave lithotripsy. / Perry Jr, Kent T; Smith, Norm D.; Weiser, Adam C.; User, Herbert M.; Kundu, Shilajit D; Nadler, Robert B.

In: Journal of Urology, Vol. 164, No. 3 I, 01.01.2000, p. 644-647.

Research output: Contribution to journalArticle

TY - JOUR

T1 - The efficacy and safety of synchronous bilateral extracorporeal shock wave lithotripsy

AU - Perry Jr, Kent T

AU - Smith, Norm D.

AU - Weiser, Adam C.

AU - User, Herbert M.

AU - Kundu, Shilajit D

AU - Nadler, Robert B

PY - 2000/1/1

Y1 - 2000/1/1

N2 - Purpose: Bilateral renal calculi have traditionally been managed by staged extracorporeal shock wave lithotripsy (ESWL) due to concern about bilateral obstruction. We evaluated the safety and efficacy of synchronous bilateral ESWL in a large series of patients treated at our institution to determine the safety and efficacy of this controversial technique in what is to our knowledge the largest series to date. Materials and Methods: We retrospectively evaluated the records of 120 patients with a mean age of 48 years who underwent bilateral synchronous ESWL between 1987 and 1996. Of the patients 71 (59%) were male. Average followup was 21 months. ESWL was performed using a Dornier HM3 lithotriptor in all cases. Intraoperative technique and postoperative factors were analyzed using the Pearson product moment correlation, the 2-tailed t test and multiple regression analysis. Results: Mean stone size was 13 and 15 mm. on the left and right sides, respectively. There was an average of 1.7 stones per renal unit. After i treatment 72 of the 120 patients (60%) were stone-free bilaterally, while 72% and 73% of left and right renal units, respectively, were also stone-free. Mean creatinine was similar preoperatively and postoperatively (1.46 and 1.41 mg./dl., respectively, p = 0.73). There was i or more complications in 18 cases. The majority of complications were minor with no long-term morbidity or death and there was no case of bilateral obstruction or renal failure. Additional procedures were required in 19 patients (16%) due to significant residual stone disease or obstruction during followup. Multiple regression analysis revealed that only patient age, a right ureteral stent and the number of shocks correlated with the complication rate. Stone size and number independently increased the probability of treatment failure and a repeat procedure (p < 0.05). Patients with stones 20 mm. or greater were at particularly high risk for treatment failure and additional procedures. A total of 27 of the 35 patients (77%) with residual calculi and 13 of the 19 (68%) requiring additional procedures were in this high risk subgroup. Conclusions: Bilateral synchronous ESWL is safe and effective monotherapy for bilateral urolithiasis. No patient had bilateral obstruction or renal failure and no deterioration of renal function was detected at followup. Knowing which patient populations are at higher risk for failure or complications may guide decision making.

AB - Purpose: Bilateral renal calculi have traditionally been managed by staged extracorporeal shock wave lithotripsy (ESWL) due to concern about bilateral obstruction. We evaluated the safety and efficacy of synchronous bilateral ESWL in a large series of patients treated at our institution to determine the safety and efficacy of this controversial technique in what is to our knowledge the largest series to date. Materials and Methods: We retrospectively evaluated the records of 120 patients with a mean age of 48 years who underwent bilateral synchronous ESWL between 1987 and 1996. Of the patients 71 (59%) were male. Average followup was 21 months. ESWL was performed using a Dornier HM3 lithotriptor in all cases. Intraoperative technique and postoperative factors were analyzed using the Pearson product moment correlation, the 2-tailed t test and multiple regression analysis. Results: Mean stone size was 13 and 15 mm. on the left and right sides, respectively. There was an average of 1.7 stones per renal unit. After i treatment 72 of the 120 patients (60%) were stone-free bilaterally, while 72% and 73% of left and right renal units, respectively, were also stone-free. Mean creatinine was similar preoperatively and postoperatively (1.46 and 1.41 mg./dl., respectively, p = 0.73). There was i or more complications in 18 cases. The majority of complications were minor with no long-term morbidity or death and there was no case of bilateral obstruction or renal failure. Additional procedures were required in 19 patients (16%) due to significant residual stone disease or obstruction during followup. Multiple regression analysis revealed that only patient age, a right ureteral stent and the number of shocks correlated with the complication rate. Stone size and number independently increased the probability of treatment failure and a repeat procedure (p < 0.05). Patients with stones 20 mm. or greater were at particularly high risk for treatment failure and additional procedures. A total of 27 of the 35 patients (77%) with residual calculi and 13 of the 19 (68%) requiring additional procedures were in this high risk subgroup. Conclusions: Bilateral synchronous ESWL is safe and effective monotherapy for bilateral urolithiasis. No patient had bilateral obstruction or renal failure and no deterioration of renal function was detected at followup. Knowing which patient populations are at higher risk for failure or complications may guide decision making.

KW - Calculi

KW - Extracorporeal shockwave lithotripsy

KW - Kidney

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