The endocrine tumor summit 2008: Appraising therapeutic approaches for acromegaly and carcinoid syndrome

Anne Klibanski*, Shlomo Melmed, David R. Clemmons, Annamaria Colao, Regina S. Cunningham, Mark E. Molitch, Aaron I. Vinik, Daphne T. Adelman, Karen J.P. Liebert

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

7 Scopus citations

Abstract

The Endocrine Tumor Summit convened in December 2008 to address 6 statements prepared by panel members that reflect important questions in the treatment of acromegaly and carcinoid syndrome. Data pertinent to each of the statements were identified through review of pertinent literature by one of the 9-member panel, enabling a critical evaluation of the statements and the evidence supporting or refuting them. Three statements addressed the validity of serum growth hormone (GH) and insulin-like growth factor-I (IGF-I) concentrations as indicators or predictors of disease in acromegaly. Statements regarding the effects of preoperative somatostatin analog use on pituitary surgical outcomes, their effects on hormone and symptom control in carcinoid syndrome, and the efficacy of extended dosing intervals were reviewed. Panel opinions, based on the level of available scientific evidence, were polled. Finally, their views were compared with those of surveyed community-based endocrinologists and neurosurgeons.

Original languageEnglish (US)
Pages (from-to)266-286
Number of pages21
JournalPituitary
Volume13
Issue number3
DOIs
StatePublished - Sep 2010

Keywords

  • Acromegaly
  • Carcinoid syndrome
  • GH
  • Growth hormone
  • IGF-I
  • Insulin-like growth factor-I
  • Lanreotide
  • NET
  • Neuroendocrine tumor
  • Octreotide
  • Somatostatin analogs
  • Somatostatin analogues

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

Fingerprint Dive into the research topics of 'The endocrine tumor summit 2008: Appraising therapeutic approaches for acromegaly and carcinoid syndrome'. Together they form a unique fingerprint.

Cite this