Abstract
The double digest problem is a common NP-hard approach to constructing physical maps of DNA sequences. This paper presents a new approach called the enhanced double digest problem. Although this new problem is also NP-hard, it can be solved in linear time in certain theoretically interesting cases.
Original language | English (US) |
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Pages (from-to) | 69-78 |
Number of pages | 10 |
Journal | Journal of Combinatorial Optimization |
Volume | 7 |
Issue number | 1 |
DOIs | |
State | Published - Mar 2003 |
Funding
∗Research supported in part by NSF Grant 9531028.
Keywords
- DNA physical mapping
- Fast algorithms
- Graph-theoretic techniques
- NP-hardness
ASJC Scopus subject areas
- Computer Science Applications
- Discrete Mathematics and Combinatorics
- Control and Optimization
- Computational Theory and Mathematics
- Applied Mathematics