The epidemiology and clinical implications of genetic variation in prostate cancer

Brian T. Helfand; William J Catalona

doi:10.1016/j.ucl.2014.01.001

The epidemiology and clinical implications of genetic variation in prostate cancer

Brian T. Helfand^*, William J Catalona

^*Corresponding author for this work

Urology

Research output: Contribution to journal › Review article › peer-review

11 Scopus citations

Abstract

There is strong evidence of a genetic predisposition to prostate cancer. Recent advances in genetic sequencing technologies have permitted significant advances in the field. This article reviews the genetic basis underlying prostate cancer, and highlights the epidemiology and potential clinical usefulness of both rare and common genetic variations. In addition, recent findings related to the understanding of prostate cancer genetics are discussed.

Original language	English (US)
Pages (from-to)	277-297
Number of pages	21
Journal	Urologic Clinics of North America
Volume	41
Issue number	2
DOIs	https://doi.org/10.1016/j.ucl.2014.01.001
State	Published - Jan 1 2014

Keywords

Genetic variants
Prostate cancer
Susceptibility
Tumor aggressiveness

ASJC Scopus subject areas

Urology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/j.ucl.2014.01.001

Cite this

@article{6e79945390e84c0db2fa210b0efa053d,

title = "The epidemiology and clinical implications of genetic variation in prostate cancer",

abstract = "There is strong evidence of a genetic predisposition to prostate cancer. Recent advances in genetic sequencing technologies have permitted significant advances in the field. This article reviews the genetic basis underlying prostate cancer, and highlights the epidemiology and potential clinical usefulness of both rare and common genetic variations. In addition, recent findings related to the understanding of prostate cancer genetics are discussed.",

keywords = "Genetic variants, Prostate cancer, Susceptibility, Tumor aggressiveness",

author = "Helfand, {Brian T.} and Catalona, {William J}",

year = "2014",

month = jan,

day = "1",

doi = "10.1016/j.ucl.2014.01.001",

language = "English (US)",

volume = "41",

pages = "277--297",

journal = "Urologic Clinics of North America",

issn = "0094-0143",

publisher = "W.B. Saunders Ltd",

number = "2",

}

TY - JOUR

T1 - The epidemiology and clinical implications of genetic variation in prostate cancer

AU - Helfand, Brian T.

AU - Catalona, William J

PY - 2014/1/1

Y1 - 2014/1/1

N2 - There is strong evidence of a genetic predisposition to prostate cancer. Recent advances in genetic sequencing technologies have permitted significant advances in the field. This article reviews the genetic basis underlying prostate cancer, and highlights the epidemiology and potential clinical usefulness of both rare and common genetic variations. In addition, recent findings related to the understanding of prostate cancer genetics are discussed.

AB - There is strong evidence of a genetic predisposition to prostate cancer. Recent advances in genetic sequencing technologies have permitted significant advances in the field. This article reviews the genetic basis underlying prostate cancer, and highlights the epidemiology and potential clinical usefulness of both rare and common genetic variations. In addition, recent findings related to the understanding of prostate cancer genetics are discussed.

KW - Genetic variants

KW - Prostate cancer

KW - Susceptibility

KW - Tumor aggressiveness

UR - http://www.scopus.com/inward/record.url?scp=84898467329&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84898467329&partnerID=8YFLogxK

U2 - 10.1016/j.ucl.2014.01.001

DO - 10.1016/j.ucl.2014.01.001

M3 - Review article

C2 - 24725490

AN - SCOPUS:84898467329

SN - 0094-0143

VL - 41

SP - 277

EP - 297

JO - Urologic Clinics of North America

JF - Urologic Clinics of North America

IS - 2

ER -

The epidemiology and clinical implications of genetic variation in prostate cancer

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this